Pyle Melissa, Stewart Suzanne L K, French Paul, Byrne Rory, Patterson Paul, Gumley Andrew, Birchwood Max, Morrison Anthony P
Psychosis Research Unit, Greater Manchester West NHS Mental Health Foundation Trust, Manchester, UK; School of Psychological Sciences, University of Manchester, Manchester, UK.
Early Interv Psychiatry. 2015 Apr;9(2):133-40. doi: 10.1111/eip.12098. Epub 2013 Dec 3.
To investigate the relationship between internalized stigma, depression, social anxiety and unusual experiences in young people considered to be at risk of developing psychosis.
A total of 288 participants meeting criteria for an at-risk mental state were recruited as part of a multisite randomized controlled trial of cognitive behavioural therapy for people meeting criteria for an at risk mental state (ARMS). The sample was assessed at baseline and 6 months using measures of at risk mental states, internalized stigma, depression and social anxiety.
The Personal Beliefs about Experiences Questionnaire was validated for use with an ARMS sample. Correlational analyses at baseline indicated significant relationships between internalized stigma and: (i) depression; (ii) social anxiety; (iii) distress associated with unusual psychological experiences; and (iv) suicidal thinking. Regression analysis indicates negative appraisals of unusual experiences contributed significantly to depression scores at 6-month follow up when controlling for baseline depression and unusual psychological experiences.
These findings suggest that internalized stigma may contribute to the development and maintenance of depression in young people at risk of psychosis.
调查内化耻辱感、抑郁、社交焦虑与被认为有患精神病风险的年轻人的异常体验之间的关系。
作为一项针对符合高危精神状态标准人群的认知行为疗法多中心随机对照试验的一部分,共招募了288名符合高危精神状态标准的参与者。在基线和6个月时使用高危精神状态、内化耻辱感、抑郁和社交焦虑的测量方法对样本进行评估。
《关于体验的个人信念问卷》经验证可用于高危精神状态样本。基线时的相关分析表明内化耻辱感与以下方面存在显著关系:(i)抑郁;(ii)社交焦虑;(iii)与异常心理体验相关的痛苦;以及(iv)自杀念头。回归分析表明,在控制基线抑郁和异常心理体验时,对异常体验的负面评价在6个月随访时对抑郁得分有显著贡献。
这些发现表明,内化耻辱感可能导致有患精神病风险的年轻人抑郁的发展和维持。