Eunice Kennedy Shriver, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Eunice Kennedy Shriver, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Immunity. 2015 Mar 17;42(3):395-6. doi: 10.1016/j.immuni.2015.02.018.
The role of co-receptor molecules in the generation of inducible regulatory T cells (iTregs) remains incompletely defined. In this issue of Immunity, Henderson et al. (2015) show that CD5 regulates iTreg cell induction by rendering emerging iTreg cells refractory to signals mediated by effector-differentiating cytokines.
共受体分子在诱导性调节性 T 细胞（iTreg）产生中的作用尚未完全确定。在本期《免疫》杂志上，Henderson 等人（2015 年）表明，CD5 通过使新出现的 iTreg 细胞对效应分化细胞因子介导的信号产生抗性，从而调节 iTreg 细胞的诱导。
