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[肺曲菌球的外科治疗结果]

[Results of surgical treatment for pulmonary aspergilloma].

作者信息

Ba P S, Ndiaye A, Diatta S, Ciss A G, Dieng P A, Gaye M, Fall M L, Ndiaye M

机构信息

Service de chirurgie cardiovasculaire et thoracique, hôpital Fann, BP 5035, Dakar, Sénégal.

出版信息

Med Sante Trop. 2015 Jan-Mar;25(1):92-6. doi: 10.1684/mst.2014.0412.

Abstract

INTRODUCTION

Aspergilloma results from the development, inside preexisting pulmonary cavities, of aspergillus spores. It is most commonly manifested by hemoptysis. The goal of this retrospective study is to report our surgical experience of this disease.

PATIENTS AND METHODS

From January 2004 to December 2008, 35 patients underwent surgery at the same center for pulmonary aspergilloma. We examined the epidemiological, clinical, paraclinical, therapeutic, and outcome data.

RESULTS

The patients' median age was 43.37 years (range: 20-70 years), 28 were male. The average time to consultation was 19.35 months (1-120 months), and all patients had a history of pulmonary tuberculosis. Hemoptysis was the symptom observed most often, in 54.3% of patients, followed by bronchorrhea. Aspergillus serology was positive for 22 patients. The standard radiological image was found in 20 patients. We performed 14 lobectomies, 1 bilobectomy, 1 segmentectomy, 1 bisegmentectomy, 3 lobectomies with segmentectomies, 1 bilobectomy with segmentectomy, and 14 pleuropneumonectomies. In one case, the pulmonary artery was damaged and repaired. The average duration of intensive care was 3.54 days (2-7 days) and of total hospitalization, 17.33 days (7-48). Complications were: empyema (3 cases), a large air leak (1 case), parietal suppuration (5 cases), and pleural effusion, which was drained (3 cases). There was no postoperative mortality. After 35 months (1-72), one case of recurrent hemoptysis by reinfestation was observed. Three patients died of respiratory failure, one at 6 months and the other two at 1 year after the surgery.

CONCLUSION

Despite the associated morbidity, surgical treatment of pulmonary aspergilloma must be proposed systematically to these subjects presenting hemoptysis.

摘要

引言

曲菌球是曲霉菌孢子在先前存在的肺空洞内生长所致。其最常见的表现为咯血。本回顾性研究的目的是报告我们对该疾病的手术经验。

患者与方法

2004年1月至2008年12月,35例患者在同一中心接受了肺曲菌球手术。我们检查了流行病学、临床、辅助检查、治疗及预后数据。

结果

患者的中位年龄为43.37岁(范围:20 - 70岁),男性28例。平均就诊时间为19.35个月(1 - 120个月),所有患者均有肺结核病史。咯血是最常观察到的症状,54.3%的患者出现,其次是支气管溢液。22例患者曲霉菌血清学呈阳性。20例患者发现了典型的影像学表现。我们进行了14例肺叶切除术、1例双叶切除术、1例肺段切除术、1例双肺段切除术、3例肺叶切除加肺段切除术、1例双叶切除加肺段切除术以及14例胸膜全肺切除术。1例患者肺动脉受损并进行了修复。重症监护的平均时长为3.54天(2 - 7天),总住院时长为17.33天(7 - 48天)。并发症包括:脓胸(3例)、大的漏气(1例)、胸壁化脓(5例)以及胸腔积液(已引流3例)。无术后死亡病例。35个月(1 - 72个月)后,观察到1例因再次感染出现复发性咯血。3例患者死于呼吸衰竭,1例在术后6个月死亡,另外2例在术后1年死亡。

结论

尽管存在相关并发症,但对于出现咯血的此类患者,必须系统地提出肺曲菌球的手术治疗方案。

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