Lloyd Jennifer, Wilson Michael L, Tenovuo Olli, Saarijärvi Simo
Consultative Group on Latin American Development and Security (COGLADES) , Montevideo, Asunción , Paraguay .
Brain Inj. 2015;29(5):539-49. doi: 10.3109/02699052.2014.1002003. Epub 2015 Mar 19.
To systematically review existing empirical evidence concerning neuropsychological, psychosocial and academic outcomes following mild and moderate TBI during childhood and adolescence.
The studies reviewed include data on 8553 children and adolescents from ages 0-18 that experienced mild and moderate TBIs. A literature search using MeSH terms for 'children' cross-referenced with terms associated with 'head injuries' and 'cognition' was conducted using Pubmed, CINAHL Plus and Scopus databases as well as other data sources to retrieve grey literature results. Articles published between 1 January 2008 and 22 April 2013 were included.
Fifty-five studies were included in the review, with multiple studies including information on both mild and moderate TBI; 46 studies focused on mild TBI outcomes and 22 studies focused on moderate TBI outcomes. The majority of outcomes were described as psychosocial (50%) or neuropsychological (40%); 51% of studies presented adverse outcomes.
The results suggest that not all children with mild or moderate TBI recover without long-term problems. Few studies followed children and adolescents with mild TBIs for extended periods of time, although it is clinically important to monitor patients over time.
系统综述有关儿童和青少年轻度及中度创伤性脑损伤（TBI）后神经心理、心理社会和学业成果的现有实证证据。
纳入综述的研究包含8553名0至18岁经历轻度和中度TBI的儿童及青少年的数据。使用医学主题词（MeSH）检索词“儿童”，并与“头部损伤”和“认知”相关检索词交叉引用，通过PubMed、CINAHL Plus和Scopus数据库以及其他数据源进行文献检索，以获取灰色文献结果。纳入2008年1月1日至2013年4月22日发表的文章。
综述纳入了55项研究，多项研究包含轻度和中度TBI的信息；46项研究聚焦于轻度TBI的结果，22项研究聚焦于中度TBI的结果。大多数结果被描述为心理社会方面（50%）或神经心理方面（40%）；51%的研究呈现出不良结果。
结果表明，并非所有轻度或中度TBI儿童都能完全康复且无长期问题。很少有研究对轻度TBI儿童和青少年进行长期随访，尽管随着时间推移监测患者具有临床重要性。
