Andler W, Horstmann W, Distelmeier P M
Klin Padiatr. 1985 Jan-Feb;197(1):58-60. doi: 10.1055/s-2008-1033927.
This report outlines the endocrine abnormalities associated with intracranial germinoma in childhood. The presence of special tumoral markers as alpha 1-fetoprotein and beta-HCG could be of diagnostic value and is important in respect to therapy control. However the reported case shows that despite known radiosensitivity and appropriate radiotherapy localized tumor relapse may arise soon after treatment.
本报告概述了儿童颅内生殖细胞瘤相关的内分泌异常情况。特殊肿瘤标志物如甲胎蛋白和β-人绒毛膜促性腺激素的存在可能具有诊断价值,且对治疗控制很重要。然而,报告的病例显示,尽管已知其对放疗敏感且进行了适当的放疗,但局部肿瘤仍可能在治疗后不久复发。