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慢性疼痛患者中强迫症的高患病率。

The high prevalence of obsessive-compulsive disorder in patients with chronic pain.

作者信息

Mehraban Ali, Shams Jamal, Moamenzade Sirous, Samimi Seyed Mehdi, Rafiee Sahar, Zademohamadi Fatemeh

机构信息

Department of Psychiatry, Shahid-Beheshti University of Medical Sciences, Tehran, Iran.

Department of anesthesiology, Shahid-Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Iran J Psychiatry. 2014 Oct;9(4):203-8.

Abstract

OBJECTIVE

Chronic pain is a common disorder with a high prevalence of psychiatric disorder that imposes a worse prognosis on both conditions. Obsessive compulsive disorder (OCD) is estimated to be the fourth most prevalent life time psychiatric disorder, but yet has gained less attention in chronic pain comorbidity researches.

METHODS

Ninety three heterogeneous chronic pain patients who attended a pain clinic in Tehran (Iran) in an outpatient setting during three months were included in this study. Diagnosis was made by Structured Clinical Interview for DSM-IV (SCID).

RESULTS

The mean age of the patients was 46.37 (SD 15.005) years; of the patients, 66.7% were female and 33.3% were male. The mean duration of pain was 34.43 (SD 51.422) months. The mean pain severity on numerical pain scale was 5.82 (SD 1.950) from 10. The mean pain site number was 3.68 (SD 3.401) from the maximum of 27 places. Furthermore, 61.3% of the participants were diagnosed with lifetime OCD, 25.8% with subclinical OCD and 61.5 % with major depressive disorder (MDD). OCD diagnosis was not correlated with MDD or pain intensity. Female gender was associated with OCD (OD; 4.182, 95% CL (1.655-10.568)). Pain intensity was correlated with MDD (P < 0.05).

CONCLUSIONS

The high prevalence of OCD was comorbidity, independent of MDD and most pain characteristics. The high prevalence of OCD may be explained by the high rate of undiagnosed cause of pain as well as cultural and local factors. Using screening tests is suggested for tackling under diagnosis and under treatment of OCD and MDD.

摘要

目的

慢性疼痛是一种常见疾病,常伴有高发性精神障碍,这两种疾病的预后都较差。强迫症(OCD)据估计是第四大常见的终生精神障碍,但在慢性疼痛合并症研究中受到的关注较少。

方法

本研究纳入了93名在德黑兰(伊朗)一家疼痛门诊接受门诊治疗的三个月内的异质性慢性疼痛患者。通过DSM-IV结构化临床访谈(SCID)进行诊断。

结果

患者的平均年龄为46.37(标准差15.005)岁;其中66.7%为女性,33.3%为男性。疼痛的平均持续时间为34.43(标准差51.422)个月。数字疼痛量表上的平均疼痛严重程度为5.82(标准差1.950)(满分10分)。平均疼痛部位数量为3.68(标准差3.401)(最多27个部位)。此外,61.3%的参与者被诊断为终生患有强迫症,25.8%为亚临床强迫症,61.5%患有重度抑郁症(MDD)。强迫症诊断与重度抑郁症或疼痛强度无关。女性与强迫症相关(比值比;4.182,95%置信区间(1.655 - 10.568))。疼痛强度与重度抑郁症相关(P < 0.05)。

结论

强迫症的高发性是合并症,独立于重度抑郁症和大多数疼痛特征。强迫症的高发性可能是由于未确诊的疼痛原因以及文化和当地因素导致的。建议使用筛查测试来解决强迫症和重度抑郁症的诊断不足和治疗不足问题。

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