Carson Henry J
Linn County Medical Examiner's Office (retired), Cedar Rapids, IA, USA.
Forensic Sci Res. 2017 Jun 30;2(3):145-151. doi: 10.1080/20961790.2017.1341364. eCollection 2017.
This study was performed to determine the relationships between chronic pain and anatomic changes that may occur in the body. Autopsies were performed on fatalities that required death investigation in Linn County, IA, or adjacent and nearby areas. Persons with chronic pain were older than the control population at the time of death. Diabetes, hypertension and depression were more common in persons with chronic pain. Certain causes of death may also have been related to chronic pain. The heart, lungs, liver, spleen and kidneys were significantly heavier in persons with chronic pain; emphysema and pleural and abdominal adhesions were more common in persons with chronic pain. There appear to have been diffuse changes in the body related to chronic pain. These changes may have been mediated by a number of systemic mechanisms that are involved with chronic pain, including cardiovascular activity, the immune system, the neuroendocrine system and others.
本研究旨在确定慢性疼痛与身体可能发生的解剖学变化之间的关系。对爱荷华州林县或邻近及周边地区需要进行死因调查的死亡者进行了尸检。慢性疼痛患者在死亡时比对照组人群年龄更大。糖尿病、高血压和抑郁症在慢性疼痛患者中更为常见。某些死因也可能与慢性疼痛有关。慢性疼痛患者的心脏、肺、肝脏、脾脏和肾脏明显更重；肺气肿以及胸膜和腹部粘连在慢性疼痛患者中更为常见。身体似乎存在与慢性疼痛相关的弥漫性变化。这些变化可能是由多种与慢性疼痛有关的全身机制介导的，包括心血管活动、免疫系统、神经内分泌系统等。
