Cortés-Dorantes N, Ruiz-Rodríguez M S, Karakowsky-Kleiman L, Garrocho-Rangel J A, Sánchez-Vargas L O, Pozos-Guillén A J
Pediatric Dentistry Postgraduate Program, Faculty of Dentistry, Universidad Autonoma de San Luis Potosí, San Luis Potosí, Mexico.
Pediatric Dentistry Postgraduate Program, Faculty of Dentistry, Universidad Tecnologica de Mexico, Mexico.
Eur J Paediatr Dent. 2015 Mar;16(1):56-60.
To assess the effect of the daily ingestion of a mixture of probiotics on the amount of Streptococcus mutans in the oral cavity of preschool-age patients with a high risk of caries.
Forty patients, aged between 4 and 6 years, with a high risk of dental caries were included in this pilot study. Patients were randomly assigned to two study groups: the Experimental Group (A) included patients who brushed their teeth and used fluoridated toothpaste in addition to consuming probiotics daily, and the Control Group (B) inclused patients who brushed their teeth and used fluoridated toothpaste but did not consume probiotics. Using the CariScreen, the microorganism count was determined at different times: baseline, 7, 14, 21 and 30 days. To identify the differences between both groups, a Mann-Whitney U test was performed, with a significance level of 0.05.
It was observed that both groups showed similar microbial counts at the beginning of the trial (p>0.05), and a significant decrease in the count at the end of the study was found in the experimental group (p<0.05) 15 days after suspending ingestion.
We found a significant reduction of RLU values in preschool children who ingested the tested probiotics in relation to the baseline values and 15 days after ceasing consumption.
评估每日摄入益生菌混合物对龋齿高风险学龄前患者口腔中变形链球菌数量的影响。
本初步研究纳入了40名年龄在4至6岁之间、患龋齿风险高的患者。患者被随机分为两个研究组：实验组（A组）包括每天刷牙、使用含氟牙膏并摄入益生菌的患者，对照组（B组）包括每天刷牙、使用含氟牙膏但不摄入益生菌的患者。使用龋易感性检测（CariScreen）在不同时间点（基线、7天、14天、21天和30天）测定微生物数量。为确定两组之间的差异，进行了曼-惠特尼U检验，显著性水平为0.05。
观察到两组在试验开始时微生物数量相似（p>0.05），在实验组中，停止摄入15天后研究结束时数量显著下降（p<0.05）。
我们发现，与基线值相比，摄入受试益生菌的学龄前儿童在停止摄入15天后，相对光单位（RLU）值显著降低。
