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DSM 17938 和 ATCC PTA 5289 在学校人群口腔健康指标中的应用:一项初步随机临床试验。

The use of DSM 17938 and ATCC PTA 5289 on oral health indexes in a school population: A pilot randomized clinical trial.

机构信息

Department of Dentistry, Faculty of Health Sciences, CEU Cardenal Herrera University, Valencia, Spain.

Department of Chemistry, Faculty of Health Sciences, CEU Cardenal Herrera University, Valencia, Spain.

出版信息

Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211031107. doi: 10.1177/20587384211031107.

Abstract

To assess the effects of a probiotic upon oral health indices in adolescents and to establish relationships between these indices and dietary habits and oral hygiene. Twenty-seven adolescents between 12 and 18 years of age were randomized into two groups. The study group received tablets containing / for 28 days, while the control group received tablets without any bacteria. sp., and salivary pH were assessed at baseline and at 7, 14, 21, 28, and 45 days. The plaque, gingivitis, and bleeding indices were recorded at baseline and at 14, 28, and 45 days. Dietary and oral hygiene habits were also evaluated by means of a questionnaire. A less marked rise in was recorded in the study group. Improvements were observed in terms of plaque, gingivitis, and bleeding, though statistical significance was not reached. Oral pH increased in the study group, though not to a significant degree. Poorer eating habits were significantly correlated to increased plaque. The study parameters decreased with the two strains of and , though the results failed to reach statistical.

摘要

评估益生菌对青少年口腔健康指数的影响,并确定这些指数与饮食习惯和口腔卫生之间的关系。将 27 名 12 至 18 岁的青少年随机分为两组。研究组服用含有 / 的片剂,共 28 天,而对照组服用不含任何细菌的片剂。在基线和第 7、14、21、28 和 45 天评估唾液 sp. 和唾液 pH 值。在基线和第 14、28 和 45 天记录菌斑、牙龈炎和出血指数。还通过问卷评估饮食和口腔卫生习惯。研究组中 sp. 的上升幅度较小。尽管未达到统计学意义,但观察到菌斑、牙龈炎和出血情况有所改善。研究组的口腔 pH 值有所升高,但升高幅度不大。不良饮食习惯与菌斑增加呈显著相关。研究参数随两种 和 的菌株减少,尽管结果未达到统计学意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2015/8327006/34f44d7b2ad7/10.1177_20587384211031107-fig1.jpg

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