Department of Orthodontics, Faculty of Dentistry, Selçuk University, Konya, Turkey.
Department of Orthodontics, Faculty of Dentistry, Selçuk University, Konya, Turkey.
Am J Orthod Dentofacial Orthop. 2018 Oct;154(4):517-523. doi: 10.1016/j.ajodo.2018.01.010.
In this study, we aimed to determine the effect of regular probiotic consumption on microbial colonization in saliva in orthodontic patients and to comparatively evaluate the difference between the systemic consumption of probiotic products and the local application.
This study included 3 groups with 15 orthodontic patients in each. The control group included patients who had no probiotic treatment, the subjects in the kefir group consumed 2 × 100 ml of kefir (Atatürk Orman Ciftligi, Ankara, Turkey) per day, and the subjects in the toothpaste group brushed their teeth with toothpaste with probiotic content (GD toothpaste; Dental Asia Manufacturing, Shah Alam, Selangor, Malaysia) twice a day. Samples were collected at 3 times: beginning of the study, 3 weeks later, and 6 weeks later. The salivary flow rate, buffer capacity, and Streptococcus mutans and Lactobacillus levels in the saliva were evaluated. Chair-side kits were used to determine the S mutans and Lactobacillus levels.
A statistically significant decrease was observed in the salivary S mutans and Lactobacillus levels in the kefir and toothpaste groups compared with the control group (P <0.05). A statistically significant increase was observed in the toothpaste group compared with the control and kefir groups in buffer capacity. Changes in the salivary flow rate were not statistically significant.
The regular use of probiotics during fixed orthodontic treatment reduces the S mutans and Lactobacillus levels in the saliva.
本研究旨在确定正畸患者中常规益生菌摄入对唾液微生物定植的影响，并比较系统摄入益生菌产品和局部应用之间的差异。
本研究包括 3 组，每组 15 名正畸患者。对照组患者未接受益生菌治疗，克菲尔组患者每天摄入 2×100ml 克菲尔（土耳其安卡拉阿塔图尔克森林农场），牙膏组患者每天使用含有益生菌的牙膏刷牙两次（GD 牙膏；马来西亚雪兰莪州沙阿兰的 Dental Asia Manufacturing）。在 3 个时间点采集样本：研究开始时、3 周后和 6 周后。评估唾液流量、缓冲能力以及唾液中的变形链球菌和乳杆菌水平。使用椅旁试剂盒确定 S 变形链球菌和乳杆菌水平。
与对照组相比，克菲尔组和牙膏组的唾液 S 变形链球菌和乳杆菌水平均显著下降（P<0.05）。与对照组和克菲尔组相比，牙膏组的缓冲能力显著增加。唾液流量的变化无统计学意义。
在固定正畸治疗期间常规使用益生菌可降低唾液中的 S 变形链球菌和乳杆菌水平。
