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种植体表面形貌对骨质疏松症兔模型中初期稳定性的影响。

Influence of implant surface topography on primary stability in a standardized osteoporosis rabbit model study.

机构信息

Department of Advanced Prosthodontics, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.

Department of Medical, Oral and Biotechnological Sciences, Chieti-Pescara University, Chieti-Via dei Vestini, 31, Chieti 66100, Italy.

出版信息

J Funct Biomater. 2015 Mar 18;6(1):143-52. doi: 10.3390/jfb6010143.

DOI:10.3390/jfb6010143
PMID:25794350
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4384105/
Abstract

Evaluating primary stability is important to predict the prognosis of dental implant treatment. Primary stability is decreased in a low bone density site such as osteoporosis. However, it is difficult to apply in small animal and the effect of the different implant surface topography for the primary stability at low bone density site has not yet fully been investigated. The purpose of the present study was to evaluate the influence of implant surface topography on primary stability in a standardized osteoporosis animal model. Six rabbits underwent ovariectomy and administrated glucocorticoid to induce an osteoporosis model. Sham-operations were performed in additional six rabbits. Implants with machined or oxidized-surfaces were inserted into the femur epiphyses and insertion torque (IT) and implant stability quotient (ISQ) were measured. In sham model, the IT and ISQ did not differ significantly between the both implant. However, the IT value of oxidized-surface implant was significantly higher than that of the machined implant in the osteoporosis model. Meanwhile, ISQ did not significantly differ between the machined and oxidized-surfaced implants. In conclusion, the IT of implants is higher with rough than with smooth surfaces but that there are no differences in ISQ value between different surfaces in a standardized osteoporosis bone reduced rabbit model.

摘要

评估初级稳定性对于预测种植牙治疗的预后非常重要。初级稳定性在骨质疏松等低骨密度部位会降低。然而，在小动物中应用起来具有难度，不同种植体表面形貌对低骨密度部位初级稳定性的影响尚未得到充分研究。本研究的目的是在标准化骨质疏松动物模型中评估种植体表面形貌对初级稳定性的影响。6 只兔子接受了卵巢切除术并给予糖皮质激素以诱导骨质疏松模型。另外 6 只兔子进行了假手术。将具有机械加工或氧化表面的种植体插入股骨骨骺，并测量了插入扭矩（IT）和种植体稳定性指数（ISQ）。在假手术模型中，两种种植体的 IT 和 ISQ 没有显著差异。然而，在骨质疏松模型中，氧化表面种植体的 IT 值明显高于机械加工种植体。同时，机械加工和氧化表面种植体的 ISQ 没有显著差异。总之，在标准化骨质疏松兔模型中，粗糙表面的种植体的 IT 比光滑表面的高，但不同表面的 ISQ 值没有差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/4384105/e66cec292a0f/jfb-06-00143-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/4384105/62b11a4ed68a/jfb-06-00143-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/4384105/380b06cd848c/jfb-06-00143-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/4384105/e66cec292a0f/jfb-06-00143-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/4384105/62b11a4ed68a/jfb-06-00143-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/4384105/2a713c39cd02/jfb-06-00143-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/4384105/e5dc015f5ea2/jfb-06-00143-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/4384105/6af58fe79a75/jfb-06-00143-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/4384105/380b06cd848c/jfb-06-00143-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/4384105/e66cec292a0f/jfb-06-00143-g006.jpg

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