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咔唑衍生物的生物活性

Biological potential of carbazole derivatives.

作者信息

Głuszyńska Agata

机构信息

Laboratory of Bioanalytical Chemistry, Faculty of Chemistry, A. Mickiewicz University, Umultowska 89b, 61-614 Poznań, Poland.

出版信息

Eur J Med Chem. 2015 Apr 13;94:405-26. doi: 10.1016/j.ejmech.2015.02.059. Epub 2015 Mar 3.

DOI:10.1016/j.ejmech.2015.02.059
PMID:25794500
Abstract

Carbazole skeleton is the key structural motif of many biologically active compounds including synthetic and natural products. Over the past several years, a large number of research highlighting the significance of carbazole derivatives has been reported in the literature. The present review focuses on the recent progress, from 2010 until now, in knowledge on various biological properties of classical, tricyclic carbazole derivatives.

摘要

咔唑骨架是许多生物活性化合物(包括合成产物和天然产物)的关键结构单元。在过去几年中,文献报道了大量突出咔唑衍生物重要性的研究。本综述聚焦于2010年至今经典三环咔唑衍生物各种生物学特性相关知识的最新进展。

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