Yin Shan, Behrman Alysha, Colvin Jonathan
Cincinnati Children's Hospital, Cincinnati, Ohio.
J Emerg Med. 2015 May;48(5):566-72. doi: 10.1016/j.jemermed.2014.12.050. Epub 2015 Mar 18.
Case reports and poison center series have highlighted increased safety concerns with laundry packs, especially when compared to traditional laundry detergents.
The purpose of this study was to examine the clinical experience with laundry pack exposures at a single institution.
A retrospective chart review was performed for exposures to laundry packs seen at a single tertiary care children's hospital medical center. Cases were identified by searching the poison center database for exposures to laundry products from March 2012 to October 2013 in children <5 years old. Medical records were reviewed for all identified cases. Data collected included demographics, treatments, laboratory and radiology data, disposition, and length of stay in the emergency department (ED).
Forty cases were included. Thirty-two were ingestions and eight were ocular exposures. Nine children were admitted, two of which were admitted to a critical care unit. Seven other children were discharged after 1-night admissions; none received any treatments after initial ED treatment. Of these, four children were admitted for the possibility of central nervous system (CNS) depression, but none showed any progression. Twenty-nine children with ingestions were discharged directly from the ED. No children had progression of CNS symptoms. Children discharged from the ED were observed a mean of 189 min.
Cases of laundry pack exposures seen at our institution were similar to cases described by US poison centers. No child had progression of CNS depression suggesting that prolonged observation is not necessary if the child does not have CNS depression at presentation.
病例报告和中毒控制中心系列研究突出了洗衣凝珠存在更多安全隐患，尤其是与传统洗衣粉相比。
本研究旨在探讨某单一机构中洗衣凝珠暴露的临床经验。
对一家三级儿童专科医院医疗中心收治的洗衣凝珠暴露病例进行回顾性病历审查。通过检索中毒控制中心数据库，找出2012年3月至2013年10月期间5岁以下儿童洗衣产品暴露病例。对所有确诊病例的病历进行审查。收集的数据包括人口统计学信息、治疗情况、实验室和放射学数据、处置方式以及在急诊科的住院时间。
共纳入40例病例。其中32例为误服，8例为眼部暴露。9名儿童住院，其中2名入住重症监护病房。另外7名儿童住院1晚后出院；在急诊科接受初始治疗后，均未接受任何其他治疗。其中，4名儿童因可能出现中枢神经系统（CNS）抑制而住院，但均未出现病情进展。29例误服儿童直接从急诊科出院。无儿童出现中枢神经系统症状进展。从急诊科出院的儿童平均观察189分钟。
我们机构所见洗衣凝珠暴露病例与美国中毒控制中心描述的病例相似。无儿童出现中枢神经系统抑制进展，这表明如果儿童就诊时无中枢神经系统抑制，则无需长时间观察。
