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孤立性右心室心肌病合并自身免疫性甲状腺功能减退症:一名青少年中的罕见关联。

Isolated right ventricular cardiomyopathy with autoimmune hypothyroidism: a rare association in an adolescent.

作者信息

Yelve Kavita, Panandikar Gajanan Ashok, Pazare Amar, Bajpai Smrati

机构信息

Department of Medicine, Seth G S Medical College and KEM Hospital, Mumbai, Maharashtra, India.

Department of General Medicine, Seth G S Medical College and KEM Hospital, Mumbai, Maharashtra, India.

出版信息

BMJ Case Rep. 2015 Mar 20;2015:bcr2014206268. doi: 10.1136/bcr-2014-206268.

DOI:10.1136/bcr-2014-206268
PMID:25795745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4368972/
Abstract

A 13-year-old girl presented with progressive dyspnoea and palpitation, diagnosed on echocardiography as primary right ventricular cardiomyopathy with atrial fibrillation. Her thyroid profile was positive for antithyroid microsomal antibody, and antithyroid peroxidase antibodies were suggestive of autoimmune hypothyroidism. She was managed with furosemide, digoxin, acenocoumarol and thyroxine following which she showed significant improvement. This is a rare case of isolated right ventricular cardiomyopathy and its association with autoimmune hypothyroidism presenting at the age of 13.

摘要

一名13岁女孩出现进行性呼吸困难和心悸,经超声心动图诊断为原发性右心室心肌病伴心房颤动。她的甲状腺检查显示抗甲状腺微粒体抗体呈阳性,抗甲状腺过氧化物酶抗体提示自身免疫性甲状腺功能减退。她接受了呋塞米、地高辛、醋硝香豆素和甲状腺素治疗,之后病情有显著改善。这是一例罕见的孤立性右心室心肌病病例,且在13岁时就出现了与自身免疫性甲状腺功能减退的关联。

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本文引用的文献

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Comparison of Uhl's anomaly, right ventricular outflow tract ventricular tachycardia (RVOT VT) & arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) with an insight into genetics of ARVD/C.Uhl 异常、右心室流出道室性心动过速(RVOT VT)和致心律失常性右室心肌病/扩张型心肌病(ARVD/C)的比较,并深入探讨 ARVD/C 的遗传学。
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Dilated cardiomyopathy: a review.扩张型心肌病:综述
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Thyroid disease and the heart.甲状腺疾病与心脏
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