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阵发性非运动诱发性运动障碍、链球菌感染后综合征与精神性运动障碍:一项诊断挑战

Paroxysmal non-kinesigenic dyskinesia, post-streptococcal syndromes and psychogenic movement disorders: a diagnostic challenge.

作者信息

Peila Elena, Mortara Paolo, Cicerale Alessandro, Pinessi Lorenzo

机构信息

Department of Neuroscience, University of Turin, Turin, Italy.

出版信息

BMJ Case Rep. 2015 Mar 20;2015:bcr2014207449. doi: 10.1136/bcr-2014-207449.

Abstract

We report a case of a 15-year-old boy presenting with sudden attacks of hyperkinetic movements of the limbs, trunk and neck. Clinical features were suggestive of paroxysmal non-kinesigenic dyskinesia, but the elevated antistreptolysin O antibody titre and history of recurrent upper airways infection led us to consider a post-streptococcal syndrome as a possible diagnosis. The patient started therapy with benzathine penicillin, sodium valproate and clonazepam without any significant improvement. A successive psychiatric assessment revealed the presence of a psychogenic movement disorder. Psychodynamic psychotherapy and individual counselling were started with progressive improvement of psychological symptoms and gradual resolution of hyperkinetic episodes, without any recurrence recorded during the follow-up (10 months).

摘要

我们报告一例15岁男孩,其出现四肢、躯干和颈部的突发运动增多性发作。临床特征提示阵发性非运动诱发性运动障碍,但抗链球菌溶血素O抗体滴度升高及反复上呼吸道感染史使我们考虑链球菌感染后综合征为可能的诊断。患者开始使用苄星青霉素、丙戊酸钠和氯硝西泮治疗,但无明显改善。随后的精神科评估显示存在精神性运动障碍。开始进行心理动力心理治疗和个体咨询,心理症状逐渐改善,运动增多发作逐渐缓解,随访(10个月)期间无复发记录。

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