Frenzel Thorsten, Krüll Andreas
Universitätsklinikum Hamburg-Eppendorf, Bereich Strahlentherapie, Ambulanzzentrum des UKE GmbH, Martinistraße 52, 20246, Hamburg, Deutschland.
Strahlenther Onkol. 2015 Nov;191(11):821-6. doi: 10.1007/s00066-015-0832-4. Epub 2015 Mar 22.
Intensity modulated radiotherapy (IMRT) is frequently used, but there are no data about current frequency regarding specific tumor sites and equipment used for quality assurance (QA).
An online survey about IMRT was executed from April to October 2014 by the collaborative IMRT working group (AK IMRT) of the German Association of Medical Physicists (DGMP).
A total of 23 German institutions took part in the survey. Most reports came from users working with Elekta, Varian, and Siemens treatment machines, but also from TomoTherapy and BrainLab. Most frequent IMRT technology was volumetric modulated arc therapy (58.37 %: VMAT/"rapid arc"), followed by step-and-shoot IMRT (14.66 %), dynamic MLC (dMLC: 14.53 %), TomoTherapy (9.25 %), and 3.2 % other techniques. Different commercial hard- and software solutions are available for QA, whereas many institutes still develop their own phantoms. Data of 26,779 patients were included in the survey; 44 % were treated using IMRT techniques. IMRT was most frequently used for anal cancer, (whole) craniospinal irradiation, head and neck cancer, prostate cancer, other tumors in the pelvic region, gynecological tumors (except for breast cancer), and brain tumors.
An estimated 10 % of all patients treated in 2014 with radiation in Germany were included in the survey. It is representative for the members of the AK IMRT.
IMRT may be on the way to replace other treatment techniques. However, many scientific questions are still open. In particular, it is unclear when the IMRT technique should not be used.
调强放射治疗(IMRT)被广泛应用,但目前尚无关于特定肿瘤部位的使用频率以及用于质量保证(QA)的设备的相关数据。
德国医学物理师协会(DGMP)的调强放射治疗协作工作组(AK IMRT)于2014年4月至10月开展了一项关于IMRT的在线调查。
共有23家德国机构参与了此次调查。大多数报告来自使用医科达、瓦里安和西门子治疗设备的用户,也有来自拓能和BrainLab的用户。最常用的IMRT技术是容积调强弧形治疗(58.37%:VMAT/“快速弧形”),其次是静态调强放射治疗(14.66%)、动态多叶准直器(dMLC:14.53%)、拓能治疗(9.25%)以及3.2%的其他技术。有不同的商业硬件和软件解决方案可用于质量保证,而许多机构仍在开发自己的模体。调查纳入了26779例患者的数据;44%的患者接受了IMRT技术治疗。IMRT最常用于肛管癌、(全)颅脊髓照射、头颈癌、前列腺癌、盆腔其他肿瘤、妇科肿瘤(乳腺癌除外)以及脑肿瘤。
据估计,2014年在德国接受放射治疗的所有患者中有10%被纳入了此次调查。该调查对AK IMRT的成员具有代表性。
IMRT可能正在逐步取代其他治疗技术。然而,许多科学问题仍未解决。特别是,目前尚不清楚何时不应使用IMRT技术。