Ren Xiao-lei, Gao Zhi-ming, Xia Hai-bo, Bao Guo-chang, Li Chun-sheng, Zhang Hao
Zhonghua Nan Ke Xue. 2015 Feb;21(2):136-9.
To sum up the clinical experience in the management of benign prostatic hyperplasia (BPH) with the prostate weighing over 80 ml by transurethral resection of the prostate (TURP) combined with 2 μm continuous-wave laser vaporesection (LVR).
We retrospectively analyzed the clinical effects of TURP combined with 2 μm LVR in the treatment of 46 cases of BPH with the prostate volume > 80 ml.
All the operations were successfully accomplished. The operation time and intraoperative blood loss were (112.0 ± 20.0) min (range 86-176 min) and (77.9 ± 25.9) ml (range 50-200 ml), respectively. The catheters were withdrawn at 7 days after surgery. Transient urinary incontinence occurred in 6 cases and secondary hemorrhage was found in 2 postoperatively. Six-month follow-up revealed no urethral stricture or other complications. Compared with the baseline, the international prostate symptom score (IPSS) was significantly decreased at 6 months after operation (26.3 ± 1.8 vs 11.6 ± 1.7, P <0.05), and so were the quality of life (QOL) score (5.3 ± 0.7 vs 1.3 ± 1.1, P <0.05) and post-void residual urine (PVR) ([115.5 ± 55.6] ml vs [19.9 ± 11.6] ml, P <0.05). However, the maximum urinary flow rate (Qmax) was remarkably increased from (4.1 ± 2.6) ml/s to (16.2 ± 1.7) ml/s (P <0.05).
TURP combined with 2 μm LVR is safe and effective for the treatment of BPH with the prostate volume >80 ml.
总结经尿道前列腺电切术（TURP）联合2μm连续波激光汽化切除术（LVR）治疗前列腺重量超过80ml的良性前列腺增生（BPH）的临床经验。
回顾性分析TURP联合2μm LVR治疗46例前列腺体积>80ml的BPH患者的临床疗效。
所有手术均顺利完成。手术时间和术中出血量分别为（112.0±20.0）分钟（范围86 - 176分钟）和（77.9±25.9）毫升（范围50 - 200毫升）。术后7天拔除导尿管。术后6例出现暂时性尿失禁，2例发生继发性出血。6个月随访未发现尿道狭窄或其他并发症。与基线相比，术后6个月国际前列腺症状评分（IPSS）显著降低（26.3±1.8 vs 11.6±1.7，P<0.05），生活质量（QOL）评分（5.3±0.7 vs 1.3±1.1，P<0.05）和残余尿量（PVR）（[115.5±55.6]毫升 vs [19.9±11.6]毫升，P<0.05）也显著降低。然而，最大尿流率（Qmax）从（4.1±2.6）毫升/秒显著增加至（16.2±1.7）毫升/秒（P<0.05）。
TURP联合2μm LVR治疗前列腺体积>80ml的BPH安全有效。
