Ravera Enrico, Schubeis Tobias, Martelli Tommaso, Fragai Marco, Parigi Giacomo, Luchinat Claudio
Center for Magnetic Resonance (CERM), University of Florence, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy; Department of Chemistry, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, Italy.
Giotto Biotech, Via Madonna del Piano 6, 50019 Sesto Fiorentino, Italy.
J Magn Reson. 2015 Apr;253:60-70. doi: 10.1016/j.jmr.2014.12.019.
Resolution and sensitivity in solid state NMR (SSNMR) can rival the results achieved by solution NMR, and even outperform them in the case of large systems. However, several factors affect the spectral quality in SSNMR samples, and not all systems turn out to be equally amenable for this methodology. In this review we attempt at analyzing the causes of this variable behavior and at providing hints to increase the chances of experimental success.
固态核磁共振（SSNMR）中的分辨率和灵敏度可与溶液核磁共振所取得的结果相媲美，在大型系统的情况下甚至优于后者。然而，有几个因素会影响SSNMR样品的光谱质量，而且并非所有系统都同样适用于这种方法。在本综述中，我们试图分析这种可变行为的原因，并提供一些提示，以增加实验成功的机会。
