Kuraishi Y, Hirota N, Sato Y, Hino Y, Satoh M, Takagi H
Brain Res. 1985 Jan 28;325(1-2):294-8. doi: 10.1016/0006-8993(85)90326-9.
Effects of various types of natural skin stimuli on the in situ release of immunoreactive substance P and somatostatin from the rabbit dorsal horn were examined. Noxious mechanical or thermal stimuli specifically increased the release of immunoreactive substance P or somatostatin, respectively. Innocuous stimuli did not affect the release of these peptides. These results suggest that the nociceptive mechanical or thermal primary afferents contain substance P or somatostatin, respectively.
研究了各种类型的天然皮肤刺激对兔背角中免疫反应性P物质和生长抑素原位释放的影响。有害的机械或热刺激分别特异性地增加了免疫反应性P物质或生长抑素的释放。无害刺激不影响这些肽的释放。这些结果表明，伤害性机械或热初级传入纤维分别含有P物质或生长抑素。
