Kimlin Michael, Sun Jiandong, Sinclair Craig, Heward Sue, Hill Jane, Dunstone Kimberley, Brodie Alison
AusSun Research Laboratory, Queensland University of Technology, Brisbane, Queensland, Australia; National Health and Medical Research Council Centre for Research Excellence in Sun and Health, Queensland University of Technology, Brisbane, Queensland, Australia.
AusSun Research Laboratory, Queensland University of Technology, Brisbane, Queensland, Australia; National Health and Medical Research Council Centre for Research Excellence in Sun and Health, Queensland University of Technology, Brisbane, Queensland, Australia.
J Steroid Biochem Mol Biol. 2016 Jan;155(Pt B):264-70. doi: 10.1016/j.jsbmb.2015.03.007. Epub 2015 Mar 20.
An adequate vitamin D status, as measured by serum 25-hydroxyvitamin D (25(OH)D) concentration, is important in humans for maintenance of healthy bones and muscle function. Serum 25(OH)D concentration was assessed in participants from Melbourne, Australia (37.81S, 144.96E), who were provided with the current Australian guidelines on sun exposure for 25(OH)D adequacy (25(OH)D ≥50 nmol/L). Participants were interviewed in February (summer, n=104) and August (winter, n=99) of 2013. Serum 25(OH)D concentration was examined as a function of measures of sun exposure and sun protection habits with control of key characteristics such as dietary intake of vitamin D, body mass index (BMI) and skin colour, that may modify this relationship. The mean 25(OH)D concentration in participants who complied with the current sun exposure guidelines was 67.3 nmol/L in summer and 41.9 nmol/L in winter. At the end of the study, 69.3% of participants who complied with the summer sun exposure guidelines were 25(OH)D adequate, while only 27.6% of participants who complied with the winter sun exposure guidelines were 25(OH)D adequate at the end of the study. The results suggest that the current Australian guidelines for sun exposure for 25(OH)D adequacy are effective for most in summer and ineffective for most in winter. This article is part of a Special Issue entitled '17th Vitamin D Workshop'.
通过血清25-羟基维生素D（25(OH)D）浓度衡量的充足维生素D状态，对人类维持健康骨骼和肌肉功能至关重要。对来自澳大利亚墨尔本（南纬37.81度，东经144.96度）的参与者的血清25(OH)D浓度进行了评估，这些参与者获得了当前澳大利亚关于充足25(OH)D的阳光照射指南（25(OH)D≥50 nmol/L）。在2013年2月（夏季，n = 104）和8月（冬季，n = 99）对参与者进行了访谈。血清25(OH)D浓度作为阳光照射措施和防晒习惯的函数进行了检查，同时控制了可能改变这种关系的关键特征，如维生素D的饮食摄入量、体重指数（BMI）和肤色。符合当前阳光照射指南的参与者中，夏季的平均25(OH)D浓度为67.3 nmol/L，冬季为41.9 nmol/L。在研究结束时，符合夏季阳光照射指南的参与者中有69.3%的人25(OH)D充足，而符合冬季阳光照射指南的参与者中在研究结束时只有27.6%的人25(OH)D充足。结果表明，当前澳大利亚关于充足25(OH)D的阳光照射指南对大多数人在夏季有效，而对大多数人在冬季无效。本文是名为“第17届维生素D研讨会”的特刊的一部分。
