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体内残留异物:国家层面的风险与后果

Retained foreign bodies: risk and outcomes at the national level.

作者信息

Al-Qurayshi Zaid H, Hauch Adam T, Slakey Douglas P, Kandil Emad

机构信息

Department of Surgery, Tulane University School of Medicine, New Orleans, LA.

Department of Surgery, Tulane University School of Medicine, New Orleans, LA.

出版信息

J Am Coll Surg. 2015 Apr;220(4):749-59. doi: 10.1016/j.jamcollsurg.2014.12.015. Epub 2014 Dec 19.

DOI:10.1016/j.jamcollsurg.2014.12.015
PMID:25797762
Abstract

BACKGROUND

Retained foreign bodies (RFB) after operative interventions are linked to an increased risk of morbidity and mortality, and represent a medico-legal liability. We aimed to identify associated risk factors and outcomes related to iatrogenic RFB in the United States.

STUDY DESIGN

A cross-sectional analysis was performed on all interventions that resulted in a secondary diagnosis of RFB in the Nationwide Inpatient Sample (NIS) from 2003 to 2009. Comparative controls were randomly selected from patients who underwent similar procedures.

RESULTS

We identified 3,045 cases of RFB, and 12,592 controls were included. The majority of incidents, 968 (31.8%), were reported after gastrointestinal interventions. Risk of RFB was higher in teaching hospitals (odds ratio [OR] 1.31, 95% CI [1.19, 1.45], p < 0.001). For abdominopelvic procedures, patients admitted with traumatic injuries did not demonstrate a higher risk of RFB compared with electively admitted patients (OR 1.70, 95% CI [0.94, 3.07], p = 0.08). However, for procedures unrelated to abdominopelvic surgery, patients admitted for trauma had a lower risk (OR 0.62, 95% CI [0.50, 0.78], p < 0.001). Obesity (BMI ≥ 30 kg/m(2)) and older age (≥ 65 years) were significantly associated with a higher risk only for abdominopelvic procedures (p < 0.01 for both). Retained foreign bodies were associated with a higher average cost of health services ($26,678.00 ± $769.69 vs $12,648.00 ± $192.80, p < 0.001).

CONCLUSIONS

Retained foreign bodies have unfavorable and nationally tangible clinical and economic outcomes. The risk profile for RFB at the national level seems to demonstrate an association with demographic and clinical factors including nature of the procedure, type of admission, and trauma status. Teaching hospitals are associated with a higher risk. Targeted efforts toward identified high-risk populations are needed to avoid these morbid and costly complications.

摘要

背景

手术干预后遗留异物(RFB)与发病率和死亡率增加相关,并且构成医疗法律责任。我们旨在确定美国医源性RFB的相关危险因素及结局。

研究设计

对2003年至2009年全国住院患者样本(NIS)中所有导致RFB二级诊断的干预措施进行横断面分析。从接受类似手术的患者中随机选取对照。

结果

我们确定了3045例RFB病例,并纳入了12592名对照。大多数事件(968例,占31.8%)是在胃肠道干预后报告的。教学医院中RFB的风险更高(比值比[OR]为1.31,95%置信区间[CI][1.19, 1.].45],p<0.001)。对于腹部盆腔手术,与择期入院患者相比,因创伤入院的患者RFB风险并未更高(OR为1.70,95%CI[0.94, 3.07],p = 0.08)。然而,对于与腹部盆腔手术无关的手术,因创伤入院的患者风险较低(OR为0.62,95%CI[0.50, 0.78],p<0.001)。肥胖(体重指数[BMI]≥30 kg/m²)和老年(≥65岁)仅在腹部盆腔手术中与较高风险显著相关(两者p均<0.01)。遗留异物与更高的平均医疗服务费用相关(26678.00美元±769.69美元对12648.00美元±192.80美元,p<0.001)。

结论

遗留异物具有不良且在全国范围内切实存在的临床和经济结局。国家层面RFB的风险特征似乎表明与人口统计学和临床因素相关,包括手术性质、入院类型和创伤状态。教学医院与之风险较高相关。需要针对已确定的高危人群采取有针对性的措施,以避免这些病态且代价高昂的并发症。

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