Groneberg Antonia H, Herget Ulrich, Ryu Soojin, De Marco Rodrigo J
Developmental Genetics of the Nervous System, Max Planck Institute for Medical Research Heidelberg, Germany.
Front Neural Circuits. 2015 Mar 6;9:9. doi: 10.3389/fncir.2015.00009. eCollection 2015.
Larval zebrafish (Danio rerio) have become favored subjects for studying the neural bases of behavior. Here, we report a highly stereotyped response of zebrafish larvae to hydrodynamic stimuli. It involves positive taxis, motion damping and sustained responsiveness to flows derived from local, non-stressful water motions. The response depends on the lateral line and has a high sensitivity to stimulus frequency and strength, sensory background and rearing conditions--also encompassing increased threshold levels of response to parallel input. The results show that zebrafish larvae can use near-field detection to locate sources of minute water motions, and offer a unique handle for analyses of hydrodynamic sensing, sensory responsiveness and arousal with accurate control of stimulus properties.
斑马鱼幼体（Danio rerio）已成为研究行为神经基础的热门对象。在此，我们报告斑马鱼幼体对流体动力刺激的一种高度刻板的反应。它包括正向趋性、运动阻尼以及对源自局部、非应激性水运动的水流的持续反应。这种反应依赖于侧线，并且对刺激频率和强度、感觉背景以及饲养条件具有高度敏感性——还包括对平行输入反应的阈值水平增加。结果表明，斑马鱼幼体能够利用近场检测来定位微小水运动的来源，并为精确控制刺激特性的流体动力传感、感觉反应性和觉醒分析提供了一个独特的切入点。
