纳米技术在胃肠道肿瘤诊断与治疗中的应用进展
Advances in the application of nanotechnology in the diagnosis and treatment of gastrointestinal tumors.
作者信息
Sun B O, Fang Yantian, Li Zhengyang, Chen Zongyou, Xiang Jianbin
机构信息
Department of General Surgery, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.
出版信息
Mol Clin Oncol. 2015 Mar;3(2):274-280. doi: 10.3892/mco.2014.470. Epub 2014 Dec 2.
Nanotechnology has broad application prospects in the diagnosis and treatment of cancer. Integrating chemistry, engineering, biology and medicine, nanotechnology is a multidisciplinary research field. Nanoscale imaging technology significantly improves the precision and accuracy of tumor diagnosis. Nanocarriers are able to significantly improve the accuracy of dose and targeted drug delivery and reduce the toxic side effects. This review focuses on the emerging roles of these innovative technologies in gastrointestinal cancer diagnostics and therapeutics. Although several problems and barriers are hampering the development of nanodevices, the potential for nanotechnologies to function as multimodal nanotheranostic agents will likely pave the way for the fight against gastrointestinal cancer.
纳米技术在癌症的诊断和治疗方面具有广阔的应用前景。纳米技术融合了化学、工程学、生物学和医学，是一个多学科的研究领域。纳米级成像技术显著提高了肿瘤诊断的精准度和准确性。纳米载体能够显著提高给药剂量的准确性和靶向给药能力，并减少毒副作用。本文综述聚焦于这些创新技术在胃肠道癌诊断和治疗中的新兴作用。尽管一些问题和障碍阻碍着纳米设备的发展，但纳米技术作为多模式纳米诊疗剂发挥作用的潜力可能会为抗击胃肠道癌铺平道路。
Zotero 插件