Kuan Edward C, Peng Kevin A, Bhuta Sunita, Diaz Miguel Fernando Palma, Zhang Zuo-Feng, Abemayor Elliot, St John Maie A
Department of Head and Neck Surgery, University of California, Los Angeles (UCLA) Medical Center, Los Angeles, CA.
Department of Pathology and Laboratory Medicine, UCLA Medical Center, Los Angeles, CA; UCLA Head and Neck Cancer Program, UCLA Medical Center, Los Angeles, CA.
Am J Otolaryngol. 2015 May-Jun;36(3):402-7. doi: 10.1016/j.amjoto.2015.01.015. Epub 2015 Jan 30.
Basaloid squamous cell carcinoma (BSCC) is a rare variant of squamous cell carcinoma characterized by a highly aggressive clinical course. Though typically found in the larynx, oropharynx, and hypopharynx, we report a rare case of BSCC originating in the maxillary sinus in an otherwise healthy 32-year-old male.
Single case report of a patient with BSCC of the maxillary sinus and retrospective chart review of all cases of BSCC of the maxilla at a single academic institution between January 1, 1986 and December 31, 2013. The MEDLINE database was additionally queried for all case series or reports of BSCC arising in the maxilla, and pertinent clinical data were extracted.
The clinical presentation, disease course, and management of a patient with BSCC of the maxilla are presented. In this recent case, the patient presented with persistent alveolar pain and a nonhealing tooth infection. Radiographic studies demonstrated a large necrotic mass in the left maxillary sinus that was biopsy-proven as BSCC. The patient underwent surgical resection followed by postoperative radiation without complications.
BSCC of the maxilla is a rare oncologic entity that may progress to late disease stage without obvious clinical signs or symptoms. Optimal treatment involves complete surgical resection followed by postoperative.
基底样鳞状细胞癌（BSCC）是鳞状细胞癌的一种罕见变体，其临床病程具有高度侵袭性。尽管通常发生于喉、口咽和下咽，但我们报告了一例罕见的起源于上颌窦的BSCC病例，患者为一名32岁的健康男性。
对上颌窦BSCC患者进行单病例报告，并对1986年1月1日至2013年12月31日期间某单一学术机构所有上颌骨BSCC病例进行回顾性病历审查。此外，检索MEDLINE数据库中所有上颌骨BSCC的病例系列或报告，并提取相关临床数据。
介绍了一名上颌骨BSCC患者的临床表现、疾病进程及治疗情况。在该近期病例中，患者表现为持续性牙槽疼痛和牙齿感染不愈合。影像学检查显示左上颌窦有一个大的坏死肿块，活检证实为BSCC。患者接受了手术切除，术后进行放疗，未出现并发症。
上颌骨BSCC是一种罕见的肿瘤实体，可能在无明显临床体征或症状的情况下进展至疾病晚期。最佳治疗方法包括完整的手术切除及术后治疗。
