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[原发性干燥综合征患者眼部染色评分增加]

[Enhanced ocular staining score in patients with primary Sjögren's syndrome].

作者信息

Sebastian Agata, Markuszewska Anna, Markuszewski Bartłomiej, Misiuk-Hojło Marta, Wiland Piotr

出版信息

Klin Oczna. 2014;116(3):205-9.

Abstract

The authors focus on the assessment of ocular manifestation in patients with primary Sjögren's syndrome using the Ocular Staining Score. The method offers the possibility to stain different ocular structures separately: cornea with fluorescein and conjunctiva with lissamine green dye and provides for separate evaluation of abnormalities, unlike the current system assessing ocular damage where ocular tissues are stained either with bengal rose or lissamine green dye. The paper presents new criteria for the diagnosis of dry eye secondary to the autoimmune Sjögren's syndrome and their high specificity (94.7% and 93.3%)ö based on the results of clinical trials in 1618 patients, conducted by an international research team.

摘要

作者们聚焦于使用眼表染色评分来评估原发性干燥综合征患者的眼部表现。该方法能够分别对不同的眼部结构进行染色:用荧光素染角膜,用丽丝胺绿染料染结膜,并能对异常情况进行单独评估,这与当前评估眼部损伤的系统不同,在当前系统中,眼部组织是用孟加拉玫瑰红或丽丝胺绿染料染色的。基于一个国际研究团队对1618名患者进行的临床试验结果,该论文提出了自身免疫性干燥综合征继发干眼症的诊断新标准,其具有很高的特异性(分别为94.7%和93.3%)。

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