Ünver Tuhan Hale, Anık Ahmet, Çatlı Gönül, Abacı Ayhan, Öztürk Tülay, Güleryüz Handan, Böber Ece
Dokuz Eylül University Faculty of Medicine, Department of Pediatric Endocrinology, İzmir, Turkey. E-mail:
J Clin Res Pediatr Endocrinol. 2015 Mar;7(1):77-9. doi: 10.4274/jcrpe.1639.
Growth hormone (GH) deficiency is the most common pituitary hormone deficiency after traumatic brain injury. Patients with GH deficiency have a reduced sweating capacity which increases the risk of developing hyperthermia. To the best of our knowledge, central fever that developed due to GH deficiency and improved with GH treatment has not yet been reported. In this article, we present a case of dramatic improvement of central fever with recombinant human GH therapy in a patient with posttraumatic GH deficiency.
生长激素（GH）缺乏是创伤性脑损伤后最常见的垂体激素缺乏症。生长激素缺乏的患者出汗能力降低，这增加了发生体温过高的风险。据我们所知，因生长激素缺乏而出现并通过生长激素治疗得到改善的中枢性发热尚未见报道。在本文中，我们报告了1例创伤后生长激素缺乏患者接受重组人生长激素治疗后中枢性发热显著改善的病例。
