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维生素D抵抗性佝偻病患者的牙周疾病

Periodontal diseases in patients with vitamin D-resistant rickets.

作者信息

Japaridze N V, Margvelashvili V V, Shengelia M I, Chigladze T T, Kalandadze M N

出版信息

Georgian Med News. 2015 Feb(239):23-6.

PMID:25802443
Abstract

OBJECTIVE

To define the risk of development of periodontal diseases at vitamin D-resistant rickets. The material for the study was based on the data from 13 children of 0-18 years with vitamin D-resistant rickets (I group), 68 children with vitamin D-dependent rickets (II group), and the control group included 61 children of the same ages. The patients were divided into 3 age groups: I group of 0-5 years (deciduous/milk teeth occlusion), II group of 6-12 of years (mixed bite), III group of 13-18 years (permanent occlusion). For the qualitative data the differences between the groups were detected by using F criteria but for the quantitative data the differences between the groups were detected by Student's t test for independent selection. Mathematical processing was performed using statistical software SPSS-22. In all three groups the gingivitis of mild and moderate forms were fixed, among them acute course was revealed only in the group of vitamin D-resistant rickets. The rate of chronic, local, catarrhal and generalized gingivitis in the group of vitamin D-resistant rickets was reliably higher in comparison with both vitamin D-dependant rickets and control groups. In addition, a mild form of periodontitis with chronic course was revealed in all three groups the rate of which was reliably higher in the group of vitamin D-resistant rickets comparing with the ones of vitamin D-dependant rickets and control groups.

CONCLUSION

the rate of inflammatory periodontal diseases in children with vitamin D-resistant rickets is higher than in children with vitamin D-dependent rickets and the control groups.

摘要

目的

确定维生素D抵抗性佝偻病患者发生牙周疾病的风险。本研究材料基于13名0至18岁维生素D抵抗性佝偻病患儿(I组)、68名维生素D依赖性佝偻病患儿(II组)的数据,对照组包括61名同年龄段儿童。患者分为3个年龄组:I组为0至5岁(乳牙/乳磨牙咬合期),II组为6至12岁(混合牙列期),III组为13至18岁(恒牙列期)。对于定性数据,采用F检验检测组间差异;对于定量数据,采用独立样本t检验检测组间差异。使用统计软件SPSS-22进行数学处理。在所有三组中均发现了轻度和中度形式的牙龈炎,其中仅在维生素D抵抗性佝偻病组中发现了急性病程。维生素D抵抗性佝偻病组慢性、局部、卡他性和广泛性牙龈炎的发生率与维生素D依赖性佝偻病组和对照组相比均显著更高。此外,在所有三组中均发现了轻度慢性牙周炎,维生素D抵抗性佝偻病组的发生率与维生素D依赖性佝偻病组和对照组相比显著更高。

结论

维生素D抵抗性佝偻病患儿炎症性牙周疾病的发生率高于维生素D依赖性佝偻病患儿和对照组。

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Dental abnormalities in patients with familial hypophosphatemic vitamin D-resistant rickets: prevention by early treatment with 1-hydroxyvitamin D.家族性低磷血症性维生素D抵抗性佝偻病患者的牙齿异常:1-羟维生素D早期治疗的预防作用
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引用本文的文献

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Could Vitamin D influence risk for Periodontal Disease - to "D" or not to "D"?维生素D会影响患牙周病的风险吗——是“维D”还是“无维D”?
Curr Oral Health Rep. 2020 Mar;7(1):98-111. doi: 10.1007/s40496-020-00253-7. Epub 2020 Jan 20.