• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

年龄不再是限制:两例90岁以上患者的肝切除术病例。

Age is no longer a limit: two cases of hepatectomy in patients over 90 years old.

作者信息

Uwatoko Shugo, Yamamoto Kentaroh, Sasaki Takamitsu, Fukumori Daisuke, Igimi Hirotsune, Yamamoto Mami, Yamamoto Fumio, Yamashita Yuichi

机构信息

Department of Surgery, Yamamoto Memorial Hospital, Imari, Japan.

Department of Gastroenterological Surgery, Fukuoka University School of Medicine, Fukuoka, Japan.

出版信息

Case Rep Gastroenterol. 2015 Feb 10;9(1):49-55. doi: 10.1159/000368115. eCollection 2015 Jan-Apr.

DOI:10.1159/000368115
PMID:25802498
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4357676/
Abstract

Hepatocellular carcinoma (HCC) is a common malignant tumor with poor prognosis. The age of patients affected by HCC is considered to be increasing, and several studies have reported significantly higher rates of morbidity and mortality after hepatectomy for HCC in elderly patients. However, other studies have reported that the short- and long-term outcomes of surgery for HCC in elderly patients are similar to those in younger patients. Whether the indications for hepatic resection in elderly patients resemble those in younger patients has thus been questioned. We describe two cases of patients over 90 years old who underwent major hepatectomy for HCC, representing the oldest patients in the world to have done so.

摘要

肝细胞癌(HCC)是一种预后较差的常见恶性肿瘤。HCC患者的年龄被认为在增加,并且有几项研究报告称,老年患者肝癌肝切除术后的发病率和死亡率显著更高。然而,其他研究报告称,老年患者肝癌手术的短期和长期结果与年轻患者相似。因此,老年患者肝切除的指征是否与年轻患者相似受到了质疑。我们描述了两例90岁以上的患者,他们接受了肝癌大肝切除术,是世界上接受该手术年龄最大的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/dcd009a9de42/crg-0009-0049-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/2ac163be9c87/crg-0009-0049-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/7e3c632bb0f8/crg-0009-0049-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/a226bb5fb561/crg-0009-0049-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/8fa89d52b64e/crg-0009-0049-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/bd281d627b00/crg-0009-0049-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/771d64411fdb/crg-0009-0049-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/dcd009a9de42/crg-0009-0049-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/2ac163be9c87/crg-0009-0049-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/7e3c632bb0f8/crg-0009-0049-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/a226bb5fb561/crg-0009-0049-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/8fa89d52b64e/crg-0009-0049-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/bd281d627b00/crg-0009-0049-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/771d64411fdb/crg-0009-0049-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edce/4357676/dcd009a9de42/crg-0009-0049-g07.jpg

相似文献

1
Age is no longer a limit: two cases of hepatectomy in patients over 90 years old.年龄不再是限制:两例90岁以上患者的肝切除术病例。
Case Rep Gastroenterol. 2015 Feb 10;9(1):49-55. doi: 10.1159/000368115. eCollection 2015 Jan-Apr.
2
Hepatic resection for hepatocellular carcinoma in elderly patients.老年患者肝细胞癌的肝切除术
Hepatogastroenterology. 2004 Jan-Feb;51(55):219-23.
3
Liver Regeneration After Major Liver Resection for Hepatocellular Carcinoma in the Elderly.老年肝细胞癌患者肝大部切除术后的肝再生
J Invest Surg. 2020 Apr;33(4):332-338. doi: 10.1080/08941939.2018.1517839. Epub 2018 Nov 2.
4
Hepatic resection for hepatocellular carcinoma in Taiwan.台湾地区肝细胞癌的肝切除术
Eur J Surg Oncol. 2002 Sep;28(6):652-6. doi: 10.1053/ejso.2002.1292.
5
Perioperative factors related to the prognosis of elderly patients with hepatocellular carcinoma.与老年肝细胞癌患者预后相关的围手术期因素。
Eur J Med Res. 2022 Dec 9;27(1):280. doi: 10.1186/s40001-022-00896-5.
6
Hepatectomy as treatment of choice for hepatocellular carcinoma in elderly cirrhotic patients.肝切除术作为老年肝硬化患者肝细胞癌的首选治疗方法。
World J Surg. 2005 Sep;29(9):1101-5. doi: 10.1007/s00268-005-7768-2.
7
Development and validation of safety and efficacy-associated risk calculator for hepatocellular carcinoma in the elderly after resection (SEARCHER): A multi-institutional observational study.老年肝细胞癌切除术后安全性和疗效相关风险计算器的开发和验证(SEARCHER):一项多机构观察性研究。
Int J Surg. 2022 Oct;106:106842. doi: 10.1016/j.ijsu.2022.106842. Epub 2022 Aug 24.
8
Safety of hepatectomy for elderly patients with hepatocellular carcinoma.老年肝细胞癌患者肝切除术的安全性
World J Gastroenterol. 2014 Nov 7;20(41):15028-36. doi: 10.3748/wjg.v20.i41.15028.
9
Hepatic resection for hepatocellular carcinoma in the elderly.老年肝细胞癌的肝切除术
J Surg Oncol. 2009 Mar 1;99(3):154-60. doi: 10.1002/jso.21221.
10
Usefulness of Preoperative Controlling Nutritional Status in Predicting Prolonged Hospitalization and Incidence of Postoperative Delirium for Elderly Hepatectomy with Hepatocellular Carcinoma.术前控制营养状况对预测老年肝细胞癌肝切除术后住院时间延长和术后谵妄发生率的作用。
Tohoku J Exp Med. 2022 Jan;256(1):43-52. doi: 10.1620/tjem.256.43.

引用本文的文献

1
Age-related changes in metabolites in young donor livers and old recipient sera after liver transplantation from young to old rats.老年受体血清与年轻供体肝脏之间的代谢物变化:年轻至老年大鼠肝脏移植后。
Aging Cell. 2021 Jul;20(7):e13425. doi: 10.1111/acel.13425. Epub 2021 Jun 22.
2
Liver resection for hepatocellular carcinoma in oldest old patients.老年患者的肝细胞癌肝切除术。
World J Surg Oncol. 2019 Jan 3;17(1):1. doi: 10.1186/s12957-018-1541-0.
3
Liver resection associated with better outcomes for single large hepatocellular carcinoma located in the same section.

本文引用的文献

1
Surgical outcomes and prognostic factors in elderly patients (75 years or older) with hepatocellular carcinoma who underwent hepatectomy.接受肝切除术的老年(75岁及以上)肝细胞癌患者的手术结果及预后因素
J Nippon Med Sch. 2013;80(6):426-32. doi: 10.1272/jnms.80.426.
2
First report of hepatectomy without endotracheal general anesthesia.首例无气管内全身麻醉的肝切除术报告。
J Am Coll Surg. 2013 May;216(5):908-14. doi: 10.1016/j.jamcollsurg.2013.01.002. Epub 2013 Mar 13.
3
Laparoscopic segmentectomy of the liver: from segment I to VIII.
对于位于同一肝段的单个大肝细胞癌,肝切除术与更好的预后相关。
Medicine (Baltimore). 2017 Mar;96(10):e6246. doi: 10.1097/MD.0000000000006246.
4
Preoperative selection of patients with colorectal cancer liver metastasis for hepatic resection.结直肠癌肝转移患者肝切除术前的选择
World J Gastroenterol. 2016 Jan 14;22(2):567-81. doi: 10.3748/wjg.v22.i2.567.
腹腔镜肝段切除术:从肝段 I 到 VIII。
Ann Surg. 2012 Dec;256(6):959-64. doi: 10.1097/SLA.0b013e31825ffed3.
4
Outcome of hepatectomy in super-elderly patients with hepatocellular carcinoma.超高龄肝细胞癌患者肝切除术的疗效。
Hepatol Res. 2012 May;42(5):454-8. doi: 10.1111/j.1872-034X.2011.00952.x. Epub 2012 Feb 1.
5
The efficacy of three transection techniques of the liver resection: a randomized clinical trial.肝切除三种横断技术的疗效:一项随机临床试验
Hepatogastroenterology. 2012 Jul-Aug;59(117):1501-6. doi: 10.5754/hge11552.
6
Liver regeneration and aging: a current perspective.肝脏再生与衰老:当前观点
Curr Gerontol Geriatr Res. 2011;2011:526379. doi: 10.1155/2011/526379. Epub 2011 Sep 8.
7
Validation of risk stratification schemes for predicting stroke and thromboembolism in patients with atrial fibrillation: nationwide cohort study.验证用于预测心房颤动患者中风和血栓栓塞风险分层方案的有效性:全国队列研究。
BMJ. 2011 Jan 31;342:d124. doi: 10.1136/bmj.d124.
8
Outcome of repeat hepatectomy in patients with hepatocellular carcinoma aged 75 years and older.75 岁及以上肝细胞癌患者再次肝切除的结果。
Surgery. 2010 May;147(5):696-703. doi: 10.1016/j.surg.2009.10.054. Epub 2009 Dec 16.
9
Aging and liver regeneration.衰老与肝脏再生
Trends Endocrinol Metab. 2009 May;20(4):171-6. doi: 10.1016/j.tem.2009.01.005. Epub 2009 Apr 7.
10
Hepatic resection for hepatocellular carcinoma in the elderly.老年肝细胞癌的肝切除术
J Surg Oncol. 2009 Mar 1;99(3):154-60. doi: 10.1002/jso.21221.