Aizawa Y, Scher A M
Pacing Clin Electrophysiol. 1985 Mar;8(2):170-4. doi: 10.1111/j.1540-8159.1985.tb05746.x.
Atrial contraction in dogs with atrioventricular (AV) block was controlled by multiple atrial stimuli delivered during ventricular diastole. Acute hemodynamic changes were assessed. At a ventricular rate of 60 bpm, the spontaneous atrial rate averaged 83, and atrial cannon waves were frequent. When the atria were given two stimuli at an interval of 500 ms during ventricular diastole, the cannon waves were eliminated completely, and a fall in mean central venous pressure and a rise in systemic blood pressure were found. At a pacing rate of 90 bpm, similar changes in the cannon waves, mean central venous pressure, and systemic blood pressure were found when two atrial stimuli followed ventricular stimulation. Ventriculo-atrial multiple pacing may be useful in both clinical and experimental AV block.
在患有房室（AV）阻滞的犬中，通过在心室舒张期给予多个心房刺激来控制心房收缩。评估急性血流动力学变化。在心室率为60次/分钟时，自发心房率平均为83次，心房大炮波频繁出现。当在心室舒张期以500毫秒的间隔给予心房两个刺激时，大炮波完全消除，同时发现平均中心静脉压下降和体循环血压升高。在起搏频率为90次/分钟时，当心室刺激后跟随两个心房刺激时，在大炮波、平均中心静脉压和体循环血压方面发现了类似的变化。心室-心房多次起搏在临床和实验性AV阻滞中可能都有用。
