Coskey R L, Feit T S, Plaia R, Zicari T
Pacing Clin Electrophysiol. 1983 May;6(3 Pt 1):631-40. doi: 10.1111/j.1540-8159.1983.tb05305.x.
Five patients with impaired left ventricular function (LV) and implanted AV sequential pacemakers underwent serial radionuclide angiograms. The goal was a non-invasive evaluation of the rapid changes in left ventricular performance elicited by rate, pacing mode and AV interval manipulation. End diastolic volume, end systolic volume, stroke volume and cardiac output were increased by AV sequential pacing in comparison with ventricular pacing at 70 beats per minute. No significant change in ejection fraction and blood pressure were noted with changing AV sequential pacing rates at usual pacing rates. Our data suggest that a short AV interval (150 ms) improved LV performance more than a long AV interval (250 ms). A non-invasive technique to optimize left ventricular performance on an acute basis by varying heart rate, AV interval and pacing mode with the implanted AV sequential pacemaker is feasible and may be useful in selective clinical situations.
五名左心室功能受损（LV）且植入了房室顺序起搏器的患者接受了系列放射性核素血管造影检查。目的是对由心率、起搏模式和房室间期操作引起的左心室功能快速变化进行无创评估。与每分钟70次心室起搏相比，房室顺序起搏使舒张末期容积、收缩末期容积、每搏量和心输出量增加。在通常起搏频率下改变房室顺序起搏频率时，射血分数和血压无显著变化。我们的数据表明，短房室间期（150毫秒）比长房室间期（250毫秒）更能改善左心室功能。通过植入的房室顺序起搏器改变心率、房室间期和起搏模式，在急性情况下优化左心室功能的无创技术是可行的，并且可能在选择性临床情况下有用。
