Yao Pei-Shui, Liu Zhanghua, Ge Jin-Zhu, Chen Yong, Cao Qian-Yong
Department of Chemistry, Nanchang University, Nanchang 330031, P. R. China.
Dalton Trans. 2015 Apr 28;44(16):7470-6. doi: 10.1039/c5dt00542f.
A hydroxyquinoline functionlized polynorbornene (P1) was designed and synthesized. In an aqueous solution, P1 shows a "turn-on" fluorescence response for Zn(2+) and Cd(2+) with a 50 nm blue shift. Furthermore, both P1-Zn(2+) and P1-Cd(2+) complexes were found to respond to pyrophosphate (PPi) over other important biological anions via a fluorescence quenching effect. P1 is also capable of monitoring intracellular Zn(2+) and PPi in real time.
设计并合成了一种羟基喹啉功能化的聚降冰片烯（P1）。在水溶液中，P1对Zn(2+)和Cd(2+)呈现“开启”荧光响应，伴有50 nm的蓝移。此外，发现P1-Zn(2+)和P1-Cd(2+)配合物通过荧光猝灭效应，相对于其他重要的生物阴离子，对焦磷酸（PPi）有响应。P1还能够实时监测细胞内的Zn(2+)和PPi。
