Sher Yelizaveta, Miller Anne Catherine, Lolak Sermsak, Ament Andrea, Maldonado José R
From the Stanford University School of Medicine, Stanford, CA (YS, AA, JRM); and the George Washington University, Washington, DC (ACM, SL).
J Neuropsychiatry Clin Neurosci. 2015 Fall;27(4):365-70. doi: 10.1176/appi.neuropsych.14080190. Epub 2015 Mar 24.
Patients with delirium may fail to respond to standard therapies. Sixteen patients with management-refractory hyperactive delirium responded to adjunctive valproic acid, with complete resolution of hyperactive delirium in 13 cases. A rationale for using valproic acid in such circumstances is discussed.
谵妄患者可能对标准治疗无反应。16例难治性躁动性谵妄患者对丙戊酸辅助治疗有反应，其中13例躁动性谵妄完全缓解。本文讨论了在这种情况下使用丙戊酸的理论依据。
