Tsakalakos N, Macfarlane C M, Taljaard J J
S Afr Med J. 1985 Apr 20;67(16):628-32.
The oxygenation status of normal and diabetic (White's classification A and B) mothers and their neonates was investigated. The diabetic patients had significantly increased maternal total haemoglobin and P50 values and the percentage of fetal haemoglobin was increased in cord blood taken at delivery in this group. There was a significant positive correlation between maternal P50 values and the percentage of fetal haemoglobin in cord blood. The cord blood 2,3-diphosphoglycerate, inorganic phosphate and P50 values were also increased in neonates born to diabetic mothers and these infants had a significantly increased birth weight ratio. The results are consistent with the presence of fetal hypoxaemia in the late third trimester of diabetic pregnancy in which obvious maternal vascular disease has been excluded.
对正常及糖尿病（怀特分类A和B）母亲及其新生儿的氧合状态进行了研究。糖尿病患者的母体总血红蛋白和P50值显著升高，且该组分娩时采集的脐血中胎儿血红蛋白百分比增加。母体P50值与脐血中胎儿血红蛋白百分比之间存在显著正相关。糖尿病母亲所生新生儿的脐血2,3-二磷酸甘油酸、无机磷酸盐和P50值也升高，且这些婴儿的出生体重比显著增加。结果表明，在排除明显母体血管疾病的糖尿病妊娠晚期存在胎儿低氧血症。
