Olesen H A, Sørensen S, Hansen P K, Mølsted-Pedersen L
Scand J Clin Lab Invest. 1984 Jun;44(4):329-34. doi: 10.3109/00365518409083815.
Haemoglobin A1c has been measured in diabetic and non-diabetic pregnant women at delivery as well as haemoglobin F adducts in paired cord blood of their infants. Haemoglobin A1c and haemoglobin F adduct estimates covariate in a group of diabetic and non-diabetic pregnant women/infants studied by ion exchange chromatography, but not when studied by isoelectric focusing. Haemoglobin A1c and birth weight ratio covariate when haemoglobin A1c is determined by isoelectric focusing but not when estimated by ion exchange chromatography. Similar results appear from the studies of others indicating that mothers' haemoglobin A1c covariates with cord blood haemoglobin F adducts and with the birth weight ratio, though correlation is scant because of extensive and efficient control of diabetic pregnant women.
已在分娩时对糖尿病和非糖尿病孕妇测量糖化血红蛋白A1c，并对其婴儿的配对脐带血中的血红蛋白F加合物进行了测量。在一组通过离子交换色谱法研究的糖尿病和非糖尿病孕妇/婴儿中，糖化血红蛋白A1c和血红蛋白F加合物估计值存在协变量关系，但通过等电聚焦法研究时则不存在。当通过等电聚焦法测定糖化血红蛋白A1c时，糖化血红蛋白A1c与出生体重比存在协变量关系，但通过离子交换色谱法估计时则不存在。其他研究也得出了类似结果，表明母亲的糖化血红蛋白A1c与脐带血血红蛋白F加合物以及出生体重比存在协变量关系，不过由于对糖尿病孕妇进行了广泛且有效的控制，相关性较弱。
