Suppr超能文献

一种基于蒸发驱动微泵的微流控装置。

A microfluidic device based on an evaporation-driven micropump.

作者信息

Nie Chuan, Frijns Arjan J H, Mandamparambil Rajesh, den Toonder Jaap M J

机构信息

Department of Mechanical Engineering, Eindhoven University of Technology, P.O. Box 513, 5600 MB, Eindhoven, The Netherlands.

出版信息

Biomed Microdevices. 2015 Apr;17(2):47. doi: 10.1007/s10544-015-9948-7.

Abstract

In this paper we introduce a microfluidic device ultimately to be applied as a wearable sweat sensor. We show proof-of-principle of the microfluidic functions of the device, namely fluid collection and continuous fluid flow pumping. A filter-paper based layer, that eventually will form the interface between the device and the skin, is used to collect the fluid (e.g., sweat) and enter this into the microfluidic device. A controllable evaporation driven pump is used to drive a continuous fluid flow through a microfluidic channel and over a sensing area. The key element of the pump is a micro-porous membrane mounted at the channel outlet, such that a pore array with a regular hexagonal arrangement is realized through which the fluid evaporates, which drives the flow within the channel. The system is completely fabricated on flexible polyethylene terephthalate (PET) foils, which can be the backbone material for flexible electronics applications, such that it is compatible with volume production approaches like Roll-to-Roll technology. The evaporation rate can be controlled by varying the outlet geometry and the temperature. The generated flows are analyzed experimentally using Particle Tracking Velocimetry (PTV). Typical results show that with 1 to 61 pores (diameter = 250 μm, pitch = 500 μm) flow rates of 7.3 × 10(-3) to 1.2 × 10(-1) μL/min are achieved. When the surface temperature is increased by 9.4°C, the flow rate is increased by 130 %. The results are theoretically analyzed using an evaporation model that includes an evaporation correction factor. The theoretical and experimental results are in good agreement.

摘要

在本文中,我们介绍了一种最终将用作可穿戴汗液传感器的微流控装置。我们展示了该装置微流控功能的原理证明,即流体收集和连续流体泵送。基于滤纸的层最终将形成装置与皮肤之间的界面,用于收集流体(如汗液)并将其引入微流控装置。可控蒸发驱动泵用于驱动连续流体流过微流控通道并经过传感区域。泵的关键元件是安装在通道出口处的微孔膜,从而实现具有规则六边形排列的孔阵列,流体通过该孔阵列蒸发,进而驱动通道内的流动。该系统完全在柔性聚对苯二甲酸乙二醇酯(PET)箔上制造,PET箔可以作为柔性电子应用的基础材料,因此它与卷对卷技术等批量生产方法兼容。蒸发速率可以通过改变出口几何形状和温度来控制。使用粒子跟踪测速法(PTV)对产生的流动进行实验分析。典型结果表明,对于1至61个孔(直径 = 250μm,间距 = 500μm),流速达到7.3×10⁻³至1.2×10⁻¹μL/min。当表面温度升高9.4°C时,流速增加130%。使用包含蒸发校正因子的蒸发模型对结果进行理论分析。理论和实验结果吻合良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eb8/4372687/80e1806cb99b/10544_2015_9948_Fig1_HTML.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验