兔肌浆网通道一个亚状态的电导和选择性特性
Conductance and selectivity properties of a substate of the rabbit sarcoplasmic reticulum channel.
作者信息
Fox J A
出版信息
Biophys J. 1985 Apr;47(4):573-6. doi: 10.1016/S0006-3495(85)83953-9.
Abstract
In this paper I describe the occurrence and properties of a subconductance state of the cation-selective channel of the sarcoplasmic reticulum. The substate conductance is 60% of the major state conductance in every salt solution examined. When single channel conductance is plotted vs. ion concentration (for potassium or thallium salt solutions) the Michaelis-Menten constant is nearly the same for both conductance states, while the maximum conductance is reduced for the subconductance state. Both conductance states show anomalous conductance behavior in mixed potassium-thallium solutions that may be modeled in the same way. These results indicate that the ionic selectivity of the channel is the same for both open states.
摘要
在本文中，我描述了肌浆网阳离子选择性通道的一种亚电导状态的出现及特性。在所检测的每种盐溶液中，亚状态电导是主要状态电导的60%。当绘制单通道电导与离子浓度（对于钾盐或铊盐溶液）的关系图时，两种电导状态的米氏常数几乎相同，而亚电导状态的最大电导降低。在混合钾 - 铊溶液中，两种电导状态均表现出异常电导行为，且这种行为可用相同方式建模。这些结果表明，对于两种开放状态，通道的离子选择性是相同的。
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本文引用的文献
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