Oh Djin-Ye, Madhusoodhan P Pallavi, Springer Deborah J, Inglima Kenneth, Chaudhri Ali A, Heitman Joseph, Raetz Elizabeth A, Khaitan Alka, Rigaud Mona
From the *Saul Krugman Division of Pediatric Infectious Diseases, Department of Pediatrics, New York University Medical School, New York, NY; †Division of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA; ‡Division of Pediatric Hematology and Oncology, Department of Pediatrics, New York University Medical School, New York, NY; §Department of Molecular Genetics and Microbiology (MGM), ¶Department of Pharmacology and Cancer Biology, and ‖Department of Medicine, Duke University Medical Center, Durham, NC; **Department of Pathology, New York University Medical School, New York, NY; and ††Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT.
Pediatr Infect Dis J. 2015 Jun;34(6):662-6. doi: 10.1097/INF.0000000000000687.
Cryptococcosis is infrequent in children, and isolated cryptococcal osteomyelitis is rarely encountered. Here, we describe a 14-year-old patient in remission from T-cell acute lymphoblastic leukemia with osteomyelitis because of Cryptococcus neoformans var. grubii. The patient was effectively treated with antifungal therapy.
隐球菌病在儿童中并不常见,孤立性隐球菌性骨髓炎更是罕见。在此,我们描述一名14岁的患者,其T细胞急性淋巴细胞白血病处于缓解期,却因新型隐球菌格鲁比变种感染而患上骨髓炎。该患者通过抗真菌治疗得到了有效治疗。