Aiello Lisa B
College of Nursing and Health Professions, Drexel University, Philadelphia, PA.
Oncol Nurs Forum. 2015 Mar;42(2):204-6. doi: 10.1188/15.ONF.204-206.
Since the completion of the Human Genome Project (HGP) in 2003, the understanding of genetics and its influence on disease, particularly cancer, has increased dramatically. The initial focus after the completion of HGP was on identifying single-gene disorders, such as many hereditary cancer syndromes (e.g., BRCA1, BRCA2, HNPCC). As research continues, the major impact that genetics and genomics have across the healthcare continuum is only beginning to become clear.
自2003年人类基因组计划(HGP)完成以来,人们对遗传学及其对疾病,尤其是癌症的影响的理解有了显著提高。HGP完成后的最初重点是识别单基因疾病,例如许多遗传性癌症综合征(如BRCA1、BRCA2、遗传性非息肉病性结直肠癌)。随着研究的持续进行,遗传学和基因组学在整个医疗保健连续过程中的重大影响才刚刚开始显现出来。