β-肾上腺素能药物治疗高钾性周期性麻痹。
beta-Adrenergic treatment of hyperkalemic periodic paralysis.
作者信息
Bendheim P E, Reale E O, Berg B O
出版信息
Neurology. 1985 May;35(5):746-9. doi: 10.1212/wnl.35.5.746.
PMID:2581176
Abstract
In a patient with hyperkalemic periodic paralysis, metaproterenol prevented muscular weakness and hyperkalemia in periods of rest after exercise. During a severe attack, the drug rapidly corrected hyperkalemia and seemed to enhance the return of strength. The action of metaproterenol may involve a beta-adrenergic-mediated increase of potassium transport via the sodium-potassium pump.
摘要
在一名高钾性周期性麻痹患者中，间羟异丙肾上腺素可预防运动后休息期间的肌肉无力和高钾血症。在严重发作期间，该药可迅速纠正高钾血症，并似乎能促进肌力恢复。间羟异丙肾上腺素的作用可能涉及β-肾上腺素能介导的通过钠钾泵增加钾转运。
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