Grosso Andrea, Pellegrini Marco, Cereda Matteo G, Panico Claudio, Staurenghi Giovanni, Sigler Eric J
*Department of Ophthalmology, Torino Eye Hospital and Centre for Macular Research and Allied Diseases, San Mauro, Italy; †Department of Biomedical and Clinical Science "Luigi Sacco", Eye Clinic, Sacco Hospital, University of Milan, Milan, Italy; ‡Department of Ophthalmology, Torino Eye Hospital, Torino, Italy; §Ophthalmic Consultants of Long Island, Division of Retina and Vitreous, Rockville Centre, New York; and ¶Ophthalmic Consultants of Long Island, Division of Retina and Vitreous, Lynbrook, New York.
Retina. 2015 Apr;35(4):614-23. doi: 10.1097/IAE.0000000000000485.
To review current literature on Coats disease and provide a structured framework for differentiating challenging clinical features in Coats disease patients.
We critically reappraise historical and current literature and present clinical methods for developing a thorough differential diagnosis and management strategy for Coats disease.
Coats disease is a sporadic, usually unilateral condition typically occurring in young males. When untreated, this disorder can lead to total exudative retinal detachment and secondary glaucoma.
Anti-VEGF agents are currently a treatment option in combination with ablative therapy of telangiectatic vessels. Anti-VEGF agents appear particularly useful for patients with extensive areas of exudative retinal detachment, and are an effective treatment option for total retinal detachment.
回顾关于科茨病的当前文献，并为区分科茨病患者具有挑战性的临床特征提供一个结构化框架。
我们严格重新评估历史和当前文献，并介绍用于制定科茨病全面鉴别诊断和管理策略的临床方法。
科茨病是一种散发性疾病，通常为单侧发病，多见于年轻男性。若不治疗，这种疾病可导致完全性渗出性视网膜脱离和继发性青光眼。
抗血管内皮生长因子（VEGF）药物目前是与扩张性血管的消融治疗联合使用的一种治疗选择。抗VEGF药物对于有大面积渗出性视网膜脱离的患者似乎特别有用，并且是完全性视网膜脱离的一种有效治疗选择。
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