Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Ophthalmologica. 2012;227(4):175-82. doi: 10.1159/000336906. Epub 2012 Mar 20.
Coats' disease is an idiopathic, ophthalmic condition characterized by retinal telangiectasis, intraretinal and subretinal exudation, which can lead to retinal detachment. It is mostly unilateral, progressive and affects mainly males during childhood, although adult cases have also been described. In this review, we make an update of the literature about Coats' disease, emphasizing on diagnosis and treatment, including the most recent treatment modalities, i.e. anti-vascular endothelial growth factor agents.
coats 病是一种特发性眼部疾病,其特征为视网膜毛细血管扩张、视网膜内和视网膜下渗出,可导致视网膜脱离。该病多为单侧、进行性,主要发生于儿童期男性,但也有成年病例的报道。本文就 coats 病的诊治,尤其是最新治疗方法(如抗血管内皮生长因子药物)进行文献复习。