从海洋生态系统中发现新型生物表面活性剂的宏基因组学。
Metagenomics for the discovery of novel biosurfactants of environmental interest from marine ecosystems.
机构信息
Marine Biotechnology Centre, Environmental Research Institute, National University of Ireland, Cork, Ireland.
Marine Biotechnology Centre, Environmental Research Institute, National University of Ireland, Cork, Ireland; School of Microbiology, University College Cork, National University of Ireland, Cork, Ireland; BIOMERIT Research Centre, University College Cork, National University of Ireland, Cork, Ireland.
出版信息
Curr Opin Biotechnol. 2015 Jun;33:176-82. doi: 10.1016/j.copbio.2015.03.004. Epub 2015 Mar 24.
Research focused on the search for new biosurfactants aims to replace chemical surfactants, which while being cost-effective are ecologically undesirable. Metagenomics can lead to discovery of novel biosurfactants, tackling issues of low production yields. Recent successes include the heterologous production of biosurfactants. The dearth of biosurfactants discovered to date through metagenomics is puzzling given that good screening systems and heterologous host systems are available.
研究集中于寻找新型生物表面活性剂，以替代虽然具有成本效益但在生态上不可取的化学表面活性剂。宏基因组学可以发现新型生物表面活性剂，解决产量低的问题。最近的成功案例包括生物表面活性剂的异源生产。考虑到现有的良好筛选系统和异源宿主系统，通过宏基因组学发现的生物表面活性剂如此之少，令人费解。
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