Yamaguchi Ryuhei, Tanaka Gaku, Liu Hao, Ujiie Hiroshi
Graduate School of Engineering, Chiba University, 1-33 Yayoicho, Inage-ku, Chiba, 263-8522, Japan.
Department of Neurosurgery, Tokyo Rosai Hospital, 4-13-21 Oomori, Ohta-ku, Tokyo, 337-8570, Japan.
Heart Vessels. 2016 Apr;31(4):622-7. doi: 10.1007/s00380-015-0665-1. Epub 2015 Mar 27.
The effect of a simple bare metal stent on repression of wall shear stress inside a model cerebral aneurysm was experimentally investigated by two-dimensional particle image velocimetry in vitro. The flow model simulated a cerebral aneurysm induced at the apex of bifurcation between the anterior cerebral artery and the anterior communicating artery. Wall shear stress was investigated using both stented and non-stented models to assess the simple stent characteristics. The flow behavior inside the stented aneurysm sac was unusual and wall shear stress was much smaller inside the aneurysm sac. Stent placement effectively repressed the temporal and spatial variations and the magnitude of wall shear stress. Hence, there is an effective possibility that would retard the progress of cerebral aneurysms by even simple stent.
通过二维粒子图像测速技术在体外实验研究了简单裸金属支架对模型脑动脉瘤内壁面剪应力抑制的影响。流动模型模拟了在前脑动脉和前交通动脉分叉处顶端诱发的脑动脉瘤。使用带支架和不带支架的模型研究壁面剪应力，以评估简单支架的特性。带支架的动脉瘤腔内的流动行为异常，动脉瘤腔内的壁面剪应力要小得多。支架置入有效地抑制了壁面剪应力的时空变化及其大小。因此，即使是简单的支架也有可能有效延缓脑动脉瘤的进展。
