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弹性对大脑前动脉脑动脉瘤内壁面剪应力的影响。

Effect of elasticity on wall shear stress inside cerebral aneurysm at anterior cerebral artery.

作者信息

Xu Lijian, Sugawara Michiko, Tanaka Gaku, Ohta Makoto, Liu Hao, Yamaguchi Ryuhei

机构信息

Graduate School of Engineering, Chiba University, Chiba, Japan.

Institute of Fluid Science, Tohoku University, Miyagi, Japan.

出版信息

Technol Health Care. 2016 May 18;24(3):349-57. doi: 10.3233/THC-161135.

DOI:10.3233/THC-161135
PMID:26835728
Abstract

BACKGROUND

Many numerical studies have been published with respect to about flow structures around cerebral aneurysm assuming to be rigid. Furthermore, there is little experimental research concerning aneurysm with elastic wall. Wall shear stress in elastic wall comparing with rigid wall should be clarified in experimental approach and verified in CFD.

OBJECTIVE

We have experimentally realized elastic aneurysm model accompanying with wall deformation. Wall shear stress was examined for both rigid and elastic aneurysm models in pulsatile flow.

METHODS

Effect of elasticity on wall shear stress inside aneurysm induced at the apex of anterior cerebral artery was experimentally examined by particle image velocimetry in vitro. In order to adjust the wall deformation, the pressure adjustment chamber was specially equipped outside the aneurysm wall.

RESULTS

Effect of elasticity on wall shear stress was noticed on the comparison with that of rigidity. Wall elasticity reduced the peak magnitude, the spatial and temporal averaged wall shear stress comparing with those of wall rigidity experimentally. These reductions were endorsed by fluid-structure interaction simulation.

CONCLUSION

Elastic wall comparing with rigid wall would reduce the peak magnitude, the spatial and temporal averaged wall shear stress acting on vascular wall.

摘要

背景

许多数值研究已经发表,内容涉及假定为刚性的脑动脉瘤周围的血流结构。此外,关于具有弹性壁的动脉瘤的实验研究很少。需要通过实验方法阐明弹性壁与刚性壁相比的壁面剪应力,并在计算流体动力学(CFD)中进行验证。

目的

我们通过实验实现了伴有壁变形的弹性动脉瘤模型。在脉动流中对刚性和弹性动脉瘤模型的壁面剪应力进行了研究。

方法

通过体外粒子图像测速技术,实验研究了弹性对大脑前动脉顶端诱发的动脉瘤内的壁面剪应力的影响。为了调节壁变形,在动脉瘤壁外专门配备了压力调节室。

结果

与刚性情况相比,注意到了弹性对壁面剪应力的影响。实验表明,与壁刚性相比,壁弹性降低了峰值大小、空间和时间平均壁面剪应力。这些降低通过流固耦合模拟得到了证实。

结论

与刚性壁相比,弹性壁会降低作用在血管壁上的峰值大小、空间和时间平均壁面剪应力。

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