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班贾抗原组(布尼亚病毒科)的数字比较血清学

Numerical comparative serology of the Bhanja antigenic group (Bunyaviridae).

作者信息

Hubálek Z, Halouzka J

出版信息

Arch Virol. 1985;84(3-4):175-80. doi: 10.1007/BF01378970.

Abstract

Antigenic relationships between the two known members of the Bhanja serogroup (Bhanja virus, 7 strains; Kismayo virus, two strains) were studied by a plaque-reduction cross-neutralization test in Vero cells, using hyperimmune mouse sera. The results were then subjected to a cluster analysis, which showed (in the form of a dendrogram) a considerable antigenic difference between the two viruses. Within Bhanja virus, the European isolates from Haemaphysalis punctata or H. sulcata ticks were antigenically indistinguishable, while the strains isolated in Africa and Asia from other tick species differed slightly from the European strains and also from each other.

摘要

利用超免疫小鼠血清,通过在非洲绿猴肾细胞中进行蚀斑减少交叉中和试验,研究了班贾血清群两个已知成员(班贾病毒,7个毒株;基斯马尤病毒,2个毒株)之间的抗原关系。然后对结果进行聚类分析(以树状图形式呈现),结果显示这两种病毒之间存在相当大的抗原差异。在班贾病毒内部,从微小牛蜱或刻点血蜱分离出的欧洲毒株在抗原性上无法区分,而在非洲和亚洲从其他蜱种分离出的毒株与欧洲毒株略有不同,且彼此之间也存在差异。

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