Baoerhan Reyilanmu, Maimaiti Mireguli
Class 2, Department of 2008 7-Year Clinical Medicine, Xinjiang Medical University, Urumqi 830054, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2015 Mar;17(3):266-9.
To investigate the risk factors for type 1 diabetes among Uygur children in Xinjiang, China, in order to provide a basis for the prevention of this disease among Uygur children in Xinjiang.
The clinical data of 94 Uygur children with type 1 diabetes (case group) and 96 Uygur children without diabetes (control group) between January, 2003 and December, 2013, were retrospectively analyzed. The risk factors for type 1 diabetes among Uyghur children in Xinjiang were explored using univariate and multivariate analyses.
According to the result of univariate analysis, there were significant differences in age, prodromal infection, residence, feeding method, time for intake of starchy foods, time for intake of high-fat foods, family history, islet-cell antibodies (ICA), insulin autoantibodies (IAA), and glutamic acid decarboxylase antibodies between the case and the control groups (P<0.05). According to the result of multivariate logistic analysis, older age, early intake of starchy foods, early intake of high-fat foods, prodromal infection, positive ICA, and positive IAA were major risk factors for type 1 diabetes, and breastfeeding was a protective factor.
Type 1 diabetes among Uyghur children in Xinjiang is caused by multiple factors. Prevention and reduction of prodromal infection, reasonable diet, and promotion of breastfeeding can reduce the risk of disease.
