Lei Rui-Ling, Maimaitiabudula Muzhapaer, Ma Yan, Huang Xia, Cao Rui, Chen Yun, Guo Jia
Nursing College, Xinjiang Medical University, Urumqi 830017, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2025 Jul 15;27(7):815-821. doi: 10.7499/j.issn.1008-8830.2410080.
To investigate the current status and influencing factors of quality of life in children and adolescents with type 1 diabetes (T1DM) in Xinjiang.
A convenience sampling method was used to select 259 children with T1DM and their primary caregivers who attended three tertiary hospitals in Xinjiang from January 2023 to February 2024. The Pediatric Quality of Life Inventory Version 4.0 Generic Core Scales (PedsQL4.0) and Pediatric Quality of Life Inventory Version 3.2 Diabetes Module (PedsQL3.2-DM) were used to assess the quality of life of the children. Information on family demographics, caregiver burden, and caregiving ability was also collected. Multiple linear regression analysis was employed to identify factors associated with the quality of life of the children.
The scores for PedsQL4.0 and PedsQL3.2-DM were 77±16 and 71±16, respectively. Both were negatively correlated with caregiver burden (<0.05) and positively correlated with caregiving ability (<0.05). Multiple linear regression analysis indicated that caregiver burden, caregiving ability, family income, and parent-child relationship were significantly associated with generic quality of life (<0.05), whereas caregiver burden, caregiving ability, disease duration, place of residence, and glycated hemoglobin level were significantly associated with diabetes-specific quality of life (<0.05).
The overall quality of life of children and adolescents with T1DM in Xinjiang is relatively low. The quality of life is influenced by a combination of factors including family caregiver burden, caregiving ability, family income, parent-child relationship, disease duration, place of residence, and glycated hemoglobin level. Strategies to improve quality of life should consider the combined impact of individual disease characteristics and family factors.
调查新疆1型糖尿病（T1DM）儿童及青少年的生活质量现状及影响因素。
采用便利抽样法，选取2023年1月至2024年2月在新疆3家三级医院就诊的259例T1DM儿童及其主要照顾者。采用儿童生活质量量表第4版通用核心量表（PedsQL4.0）和儿童生活质量量表第3.2版糖尿病模块（PedsQL3.2-DM）评估儿童的生活质量。同时收集家庭人口统计学信息、照顾者负担及照顾能力等资料。采用多元线性回归分析确定与儿童生活质量相关的因素。
PedsQL4.0和PedsQL3.2-DM的得分分别为77±16和71±16。二者均与照顾者负担呈负相关（<0.05），与照顾能力呈正相关（<0.05）。多元线性回归分析表明，照顾者负担、照顾能力、家庭收入及亲子关系与总体生活质量显著相关（<0.05），而照顾者负担、照顾能力、病程、居住地及糖化血红蛋白水平与糖尿病特异性生活质量显著相关（<0.05）。
新疆T1DM儿童及青少年的总体生活质量相对较低。生活质量受多种因素综合影响，包括家庭照顾者负担、照顾能力、家庭收入、亲子关系、病程、居住地及糖化血红蛋白水平。改善生活质量的策略应考虑个体疾病特征和家庭因素的综合影响。
