Lindequist Ulrike, Jülich Wolf-Dieter, Witt Sabine
University Greifswald, Institute for Pharmacy, D-17487 Greifswald, Germany.
Biometec GmbH, Walther-Rathenau-Str. 49a, D-17489 Greifswald, Germany.
Phytochemistry. 2015 Jun;114:102-8. doi: 10.1016/j.phytochem.2015.02.018. Epub 2015 Mar 25.
In contrast to well-studied and broadly used Ganoderma species, such as Ganoderma lucidum and Ganoderma applanatum, knowledge regarding Ganoderma pfeifferi is very limited. Herein is an overview of the phytochemistry, biological activities and possible applications of this mushroom species. In addition to triterpenoids and polysaccharides, G. pfeifferi contains unique sesquiterpenoids and other small molecular weight compounds. Some of these compounds exhibit remarkable antimicrobial activities in vitro and in vivo against multi-resistant bacteria, such as MRSA. Antiviral properties, UV-protection abilities and other activities are also known. Potential issues arising from the conversion of research results into practical applications are discussed.
与深入研究且广泛使用的灵芝种类（如赤芝和树舌灵芝）相比，关于费氏灵芝的知识非常有限。本文概述了该蘑菇种类的植物化学、生物活性及可能的应用。除了三萜类化合物和多糖外，费氏灵芝还含有独特的倍半萜类化合物和其他小分子化合物。其中一些化合物在体外和体内对多重耐药细菌（如耐甲氧西林金黄色葡萄球菌）表现出显著的抗菌活性。其抗病毒特性、紫外线防护能力及其他活性也为人所知。文中还讨论了将研究成果转化为实际应用时可能出现的问题。
