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本文引用的文献

1
Phase I study of quizartinib administered daily to patients with relapsed or refractory acute myeloid leukemia irrespective of FMS-like tyrosine kinase 3-internal tandem duplication status.每日给予复发或难治性急性髓系白血病患者quizartinib 的 I 期研究,无论 FMS 样酪氨酸激酶 3 内部串联重复状态如何。
J Clin Oncol. 2013 Oct 10;31(29):3681-7. doi: 10.1200/JCO.2013.48.8783. Epub 2013 Sep 3.
2
Sorafenib in combination with intensive chemotherapy in elderly patients with acute myeloid leukemia: results from a randomized, placebo-controlled trial.索拉非尼联合强化化疗治疗老年急性髓系白血病:一项随机、安慰剂对照试验的结果。
J Clin Oncol. 2013 Sep 1;31(25):3110-8. doi: 10.1200/JCO.2012.46.4990. Epub 2013 Jul 29.
3
Phase 2 study of azacytidine plus sorafenib in patients with acute myeloid leukemia and FLT-3 internal tandem duplication mutation.阿扎胞苷联合索拉非尼治疗伴有 FLT3 内部串联重复突变的急性髓系白血病的 2 期研究。
Blood. 2013 Jun 6;121(23):4655-62. doi: 10.1182/blood-2013-01-480228. Epub 2013 Apr 23.
4
FLT3 mutations in myelodysplastic syndrome and chronic myelomonocytic leukemia.FLT3 突变在骨髓增生异常综合征和慢性粒单核细胞白血病中的作用。
Am J Hematol. 2013 Jan;88(1):56-9. doi: 10.1002/ajh.23345. Epub 2012 Oct 31.
5
FLT3 inhibition: a moving and evolving target in acute myeloid leukaemia.FLT3 抑制:急性髓系白血病中不断变化的治疗靶点。
Leukemia. 2013 Feb;27(2):260-8. doi: 10.1038/leu.2012.195. Epub 2012 Jul 16.
6
Phase IB study of the FLT3 kinase inhibitor midostaurin with chemotherapy in younger newly diagnosed adult patients with acute myeloid leukemia.一项在年轻初诊成人急性髓系白血病患者中进行的与化疗联用的 FLT3 激酶抑制剂米哚妥林的 Ib 期研究。
Leukemia. 2012 Sep;26(9):2061-8. doi: 10.1038/leu.2012.115. Epub 2012 Apr 27.
7
Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation.索拉非尼治疗 FLT3-ITD(+) 急性髓系白血病:有利的初始结果和随后无反应的机制与 D835 突变的出现有关。
Blood. 2012 May 31;119(22):5133-43. doi: 10.1182/blood-2011-06-363960. Epub 2012 Feb 24.
8
Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML).阿扎胞苷可增强急性髓系白血病(AML)患者异基因干细胞移植后调节性 T 细胞的扩增。
Blood. 2012 Apr 5;119(14):3361-9. doi: 10.1182/blood-2011-09-377044. Epub 2012 Jan 10.
9
Phase IIB trial of oral Midostaurin (PKC412), the FMS-like tyrosine kinase 3 receptor (FLT3) and multi-targeted kinase inhibitor, in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome with either wild-type or mutated FLT3.口服 Midostaurin(PKC412)、FMS 样酪氨酸激酶 3 受体(FLT3)和多靶点激酶抑制剂的 IIB 期临床试验,用于治疗伴有野生型或突变型 FLT3 的急性髓系白血病和高危骨髓增生异常综合征患者。
J Clin Oncol. 2010 Oct 1;28(28):4339-45. doi: 10.1200/JCO.2010.28.9678. Epub 2010 Aug 23.
10
Maintenance therapy with low-dose azacitidine after allogeneic hematopoietic stem cell transplantation for recurrent acute myelogenous leukemia or myelodysplastic syndrome: a dose and schedule finding study.异基因造血干细胞移植后低剂量阿扎胞苷维持治疗复发性急性髓系白血病或骨髓增生异常综合征:剂量和方案发现研究。
Cancer. 2010 Dec 1;116(23):5420-31. doi: 10.1002/cncr.25500. Epub 2010 Jul 29.

Azacitidine as post-remission consolidation for sorafenib-induced remission of Fms-like tyrosine kinase-3 internal tandem duplication positive acute myeloid leukemia.

作者信息

Gill Harinder, Man Cheuk-Him, Ip Alvin H W, Choi William W L, Chow Howard C H, Kwong Yok-Lam, Leung Anskar Y H

机构信息

Division of Haematology, Medical Oncology and Bone Marrow Transplantation, Department of Medicine, the University of Hong Kong, China.

Department of Pathology, the University of Hong Kong, China.

出版信息

Haematologica. 2015 Jul;100(7):e250-3. doi: 10.3324/haematol.2014.123034. Epub 2015 Mar 27.

DOI:10.3324/haematol.2014.123034
PMID:25820334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4486234/
Abstract
摘要