Lenke R R, Ashwood E R, Cyr D R, Gravett M, Smith J R, Stenchever M A
Obstet Gynecol. 1985 Jun;65(6):798-801.
Simultaneous ultrasound was used to determine if there was a correlation between visualized intraamniotic bleeding, placental location, and fetal-maternal hemorrhage. It was hoped to then determine which Rh-negative patients should receive Rh immunoglobulin. Visualized intraamniotic bleeding showed no correlation to fetal-maternal hemorrhage. Intraamniotic bleeding was commonly associated with needle insertion through an anterior placenta, but also occurred regardless of placental location and in the absence of placental needle traversal. No correlation was found between placental location and fetal-maternal hemorrhage as evidenced by evaluation of maternal serum alpha-fetoprotein. The Kleihauer test was not as sensitive as alpha-fetoprotein.
同时使用超声来确定可视化的羊膜腔内出血、胎盘位置和胎儿-母体出血之间是否存在关联。随后希望确定哪些Rh阴性患者应接受Rh免疫球蛋白治疗。可视化的羊膜腔内出血与胎儿-母体出血无相关性。羊膜腔内出血通常与穿刺针穿过前置胎盘有关，但也会在不考虑胎盘位置且穿刺针未穿过胎盘的情况下发生。通过评估母体血清甲胎蛋白发现，胎盘位置与胎儿-母体出血之间无相关性。克莱豪尔试验不如甲胎蛋白敏感。
